Results 71 to 80 of about 373,199 (312)

Approximation of electronic term of diatomic molecule by the Morse function. The role of anharmonicity

open access: yes, 2023
This article presents an extension of the report made at the 2nd International Symposium "Non-Covalent Interactions" 10/14/22 in Moscow. That report outlined the basic principles of modeling the potential function of diatomic molecules using the Morse ...
Gleb S., Denisov, Ruslan E., Asfin
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Function approximation using combined unsupervised and supervised learning

open access: yes, 2014
Function approximation is one of the core tasks that are solved using neural networks in the context of many engineering problems. However, good approximation results need good sampling of the data space, which usually requires exponentially increasing ...
Andras, Peter
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Deep Nets for Local Manifold Learning

open access: yesFrontiers in Applied Mathematics and Statistics, 2018
The problem of extending a function f defined on a training data C on an unknown manifold 𝕏 to the entire manifold and a tubular neighborhood of this manifold is considered in this paper. For 𝕏 embedded in a high dimensional ambient Euclidean space ℝD, a
Charles K. Chui, Hrushikesh N. Mhaskar
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

APPROXIMATION PROPERTIES OF SOME DISCRETE FOURIER SUMS FOR PIECEWISE SMOOTH DISCONTINUOUS FUNCTIONS

open access: yesПроблемы анализа, 2019
Denote by Ln, N (f, x) a trigonometric polynomial of order at most n possessing the least quadratic deviation from f with respect to the system  tk = u + 2πk N N−1 k=0 , where u ∈ R and n 6 N/2.
G. G. Akniyev
doaj   +1 more source

Metrical Approximations of Functions

open access: yesFunkcialaj Ekvacioj
In this paper, we analyze metrical approximations of functions $F :Λtimes X \rightarrow Y$ by trigonometric polynomials and $ρ$-periodic type functions, where $\emptyset \neq Λ\subseteq {\mathbb R}^{n},$ $X$ and $Y $are complex Banach spaces, and $ρ$ is a general binary relation on $Y .$ Besides the classical concept, we analyze Stepanov,Weyl ...
Chaouchi, Belkacem   +2 more
openaire   +2 more sources

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