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Mitochondrial Function, Biology, and Role in Disease: A Scientific Statement From the American Heart Association. [PDF]
Cardiovascular disease is a major leading cause of morbidity and mortality in the United States and elsewhere. Alterations in mitochondrial function are increasingly being recognized as a contributing factor in myocardial infarction and in patients ...
Murphy E+14 more
europepmc +2 more sources
Role of transforming growth factor Beta in corneal function, biology and pathology. [PDF]
Transforming growth factor-beta (TGFbeta) is a pleiotropic multifunctional cytokine that regulates several essential cellular processes in many parts of the body including the cornea.
Tandon A+4 more
europepmc +2 more sources
Metacognition: computation, biology and function [PDF]
Many complex systems maintain a self-referential check and balance. In animals, such reflective monitoring and control processes have been grouped under the rubric of metacognition.
Christopher D. Frith+10 more
core +6 more sources
Biology and Function of miR159 in Plants [PDF]
MicroR159 (miR159) is ancient, being present in the majority of land plants where it targets a class of regulatory genes called GAMYB or GAMYB-like via highly conserved miR159-binding sites. These GAMYB genes encode R2R3 MYB domain transcription factors that transduce the gibberellin (GA) signal in the seed aleurone and the anther tapetum.
Anthony A. Millar, Allan Lohe, Gigi Wong
openaire +6 more sources
Mitochondria Biology in Reproductive Function
Mitochondria are multitasking organelles involved in the maintenance of cell homeostasis [...]
Carla Tatone, Giovanna Di Emidio
doaj +4 more sources
The biology and function of exosomes in cancer [PDF]
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of extracellular vesicles released by all cells, with a size range of 40-150 nm and a lipid bilayer membrane. Exosomes contain DNA, RNA, and proteins. Exosomes likely remove excess and/or unnecessary constituents from the cells, functioning like garbage bags, although their ...
R. Kalluri
openaire +4 more sources
Periostin: biology and function in cancer
Periostin (POSTN), a member of the matricellular protein family, is a secreted adhesion-related protein produced in the periosteum and periodontal ligaments.
Shima Dorafshan+5 more
doaj +3 more sources
Molecular biology II: protein function [PDF]
DNA may be viewed as the blueprint for the body, with mRNA/protein the component parts made from this blueprint. However, it is only when proteins are allowed to interact with each other and their surroundings that true biological complexity is achieved.
Plant, N
core +10 more sources
A general introduction to glucocorticoid biology [PDF]
Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their broad physiological and therapeutic effects, GCs bind to the GC receptor (GR) which belongs to the nuclear receptor ...
Libert, Claude+2 more
core +2 more sources
microRNAs function in CD8+T cell biology
During an immune response, CD8+T cells can differentiate into multiple types of effector and memory cells that are important components of immune surveillance.
Yan Liang+2 more
openalex +3 more sources