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Periostin: biology and function in cancer
Periostin (POSTN), a member of the matricellular protein family, is a secreted adhesion-related protein produced in the periosteum and periodontal ligaments.
Shima Dorafshan+5 more
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Mitochondria Biology in Reproductive Function
Mitochondria are multitasking organelles involved in the maintenance of cell homeostasis [...]
Carla Tatone, Giovanna Di Emidio
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Molecular biology II: protein function [PDF]
DNA may be viewed as the blueprint for the body, with mRNA/protein the component parts made from this blueprint. However, it is only when proteins are allowed to interact with each other and their surroundings that true biological complexity is achieved.
Plant, N
core +10 more sources
AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan+12 more
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Abstract In 1966 Francis Crick declared that: “The ultimate aim of the modern movement in biology is to explain all biology in terms of physics and chemistry.” This motivated us to contemplate approaches that unify biology at a fundamental level. Exploration led us to consider the features of energy, entropy, and motion.
Lauren Gerard Koch, Steven L Britton
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In the quest for more effective radiation treatment options that can improve both cell killing and healthy tissue recovery, combined radiation therapies are lately in the spotlight.
Pilar López-Nieva+8 more
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In the recent years, the application of new antitumor drugs has focused on the replacement of conventional chemotherapeutics with compounds derived from natural products.
Jordana Todorova+4 more
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Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes
Thermogenic adipocytes maintain body temperature in response to cold, but how this is tuned during cold and re-warming is unclear. Here, the authors show HIF2α inhibits beige adipocyte retention, regulating PKA catalysis to control dynamic adipocyte ...
Ji Seul Han+14 more
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Metacognition: computation, biology and function [PDF]
Many complex systems maintain a self-referential check and balance. In animals, such reflective monitoring and control processes have been grouped under the rubric of metacognition. In this introductory article to a Theme Issue on metacognition, we review recent and rapidly progressing developments from neuroscience, cognitive psychology, computer ...
Raymond J. Dolan+4 more
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By interacting with the mRNA 5′ cap, the translation initiation factor eIF4E plays a critical role in selecting mRNAs for protein synthesis in eukaryotic cells.
Ebelechukwu C. Nwokoye+6 more
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