Results 111 to 120 of about 14,894,566 (393)
The biology, function, and applications of exosomes in cancer
Acta Pharmaceutica Sinica B, 2021 Jin-yi Liu +9 more
semanticscholar +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
AdipocyteIn mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism.
Yong Geun Jeon, Sun Won Kim, Jae Bum Kim
doaj +1 more source
Interaction of the pioneer transcription factor GATA3 with nucleosomes
Nature Communications, 2020 GATA 3 functions as a pioneer factor during cellular reprogramming. Here the authors delineate nucleosome positioning relative to GATA3 binding motifs and describe the structure of a GATA3–nucleosome complex; providing insight into how a pioneer factor ...
Hiroki Tanaka +7 more
doaj +1 more source
The Fungal Cell Wall: Structure, Biosynthesis, and Function
Microbiology spectrum, 2017 The molecular composition of the cell wall is critical for the biology and ecology of each fungal species. Fungal walls are composed of matrix components that are embedded and linked to scaffolds of fibrous load-bearing polysaccharides. Most of the major
N. Gow, J. Latgé, C. Munro
semanticscholar +1 more source
Systems biology to predict blood function [PDF]
Journal of Thrombosis and Haemostasis, 2009 Systems biology seeks to provide a quantitative framework to understand blood as a reactive biological fluid whose function is dictated by prevailing haemodynamics, vessel wall characteristics, platelet metabolism, numerous coagulation factors in plasma, and small molecules released during thrombosis.
openaire +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Evolution strategies in optimization problems [PDF]
, 2007 Evolution strategies are inspired in biology and form part of a larger research field known as evolutionary algorithms. Those strategies perform a random search in the space of admissible functions, aiming to optimize some given objective function.
Cruz, P.A.F., Torres, D.F.M.
core +1 more source
Glia as architects of central nervous system formation and function
Science, 2018 Glia constitute roughly half of the cells of the central nervous system (CNS) but were long-considered to be static bystanders to its formation and function.
N. J. Allen, D. Lyons
semanticscholar +1 more source