Results 221 to 230 of about 3,596,843 (342)

Disruption of photoreceptor cilia is a critical event in the pathogenesis of retinal degeneration—Insights from N-methyl-N-nitrosourea-induced mouse model

Medicine Plus
Guizhi Guo, Runa Wang, Yufei Zhang, Zhiyi Wang, Lin Li, Miaoyuan Liu, Jun Zhou, Jie Ran   +7 more
doaj   +1 more source

Effects of Biodiversity Loss on Freshwater Ecosystem Functions Increase With the Number of Stressors. [PDF]

Glob Chang Biol
Schäfer RB, Baikova D, Bayat HS, Beermann AJ, Berger SA, Boenigk J, Brauns M, Burfeid-Castellanos A, Cardinale BJ, David GM, Feckler A, Feld CK, Fink P, Gessner MO, Hadziomerovic U, Hering D, Le TTY, Macaulay SJ, Madariaga GM, Serge Mayombo NA, Pimentel IM, Orr JA, Osakpolor S, Schlenker A, Sures B, Vermiert AM, Vos M, Weitere M, Schürings C.   +28 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Proteomics Approaches to Ecoimmunology: New Insights into Wildlife Immunity and Disease. [PDF]

Integr Comp Biol
Vicente-Santos A, Sandoval-Herrera N, Czirják GÁ, Neely BA, Becker DJ.   +4 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Sphingosine 1-phosphate signalling in cancer stem cells. [PDF]

Oncogenesis
Powell JA, Pitson SM.
europepmc   +1 more source

Vascular endothelial growth factor D : biology and function in transgenic and knockdown mice

, 2020
Antti Kotimaa
openalex   +1 more source

1E1524 Development of a scoring function for domain-domain docking to predict multi-domain protein structures(Genome biology, Bioinformatics,The 49th Annual Meeting of the Biophysical Society of Japan)

, 2011
Satoru Hirako, Masafumi Shionyu
openalex   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Correction: GP73-mediated secretion of PKM2 and GP73 promotes angiogenesis and M2-like macrophage polarization in hepatocellular carcinoma

Cell Death and Disease
Shujie Wang, Tongjia Zhang, Yue Zhou, Zitao Jiao, Kejia Lu, Xinyi Liu, Wei Jiang, Zhe Yang, Hui Li, Xiaowei Zhang   +9 more
doaj   +1 more source