Results 31 to 40 of about 14,637,911 (412)

A structural biology community assessment of AlphaFold2 applications

open access: yesbioRxiv, 2021
Most proteins fold into 3D structures that determine how they function and orchestrate the biological processes of the cell. Recent developments in computational methods have led to protein structure predictions that have reached the accuracy of ...
Mehmet Akdel   +30 more
semanticscholar   +1 more source

Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling

open access: yesExperimental and Molecular Medicine, 2018
Colorectal cancer: Finding new small molecule drug candidates Mutations in KRAS, a gene regulating cell proliferation, occur in 40–50% of colorectal cancer (CRC) patients.
Wookjin Shin   +8 more
doaj   +1 more source

The Effect of Milk Replacer Composition on the Intestinal Microbiota of Pre-ruminant Dairy Calves

open access: yesFrontiers in Veterinary Science, 2019
The impact of dietary composition and prebiotics, in promoting the growth of beneficial groups of gut bacteria, is increasingly apparent. Using Illumina MiSeq sequencing of bacterial 16S rRNA genes, this study has aimed to characterize and compare the ...
James Badman   +7 more
doaj   +1 more source

Tolerance of Capsicum frutescens L. (Solanales: Solanaceae) to the duration of waterlogging and impact on the post-waterlogging and recovery periods

open access: yesNatural History Sciences, 2023
Waterlogging is a shallow flooding in the area of the root and in some parts of the shoot. It is one of the most common types of flooding in agricultural areas.
Endang Saptiningsih   +2 more
doaj   +1 more source

Her2 Ile655Val polymorphism and its association with breast cancer risk: an updated meta-analysis of case-control studies

open access: yesScientific Reports, 2018
Breast cancer (BC) is one of the most common types of cancer in women worldwide. Several factors including genetic and environmental have been linked with susceptibility to development of BC. Her2 is a transmembrane protein with tyrosine kinase activity,
B. Madhu Krishna   +4 more
doaj   +1 more source

Utilization of Snakehead Fish Meat for Increasing Kidney Function in Rat Experiencing Physiological Stress

open access: yesBiosaintifika: Journal of Biology & Biology Education, 2018
Physiological stress for a long time can lead to impaired kidney organ function. Snakehead fish meat are known to contain important nutrients such as albumin, glutamine, glycine, cysteine, and various minerals that can improve kidney function. This study
Sunarno Sunarno   +2 more
doaj   +1 more source

Three facets of mathematical cancer biology research [PDF]

open access: yesarXiv, 2023
Cancer, as the uncontrollable cell growth, is related to many branches of biology. In this review, we will discuss three mathematical approaches for studying cancer biology: population dynamics, gene regulation, and developmental biology. If we understand all biochemical mechanisms of cancer cells, we can directly calculate how the cancer cell ...
arxiv  

Hybridization is a recurrent evolutionary stimulus in wild yeast speciation

open access: yesNature Communications, 2019
Hybridization can contribute to diversity from the genomic to the species level. Here, Eberlein, Hénault et al. investigate genomic, transcriptomic and phenotypic variation among wild lineages of the yeast Saccharomyces paradoxus and suggest that an ...
Chris Eberlein   +7 more
doaj   +1 more source

Approximation of Intractable Likelihood Functions in Systems Biology via Normalizing Flows [PDF]

open access: yesarXiv, 2023
Systems biology relies on mathematical models that often involve complex and intractable likelihood functions, posing challenges for efficient inference and model selection. Generative models, such as normalizing flows, have shown remarkable ability in approximating complex distributions in various domains. However, their application in systems biology
arxiv  

Author Correction: Hybridization is a recurrent evolutionary stimulus in wild yeast speciation

open access: yesNature Communications, 2019
The original version of the Supplementary Information associated with this Article contained errors in Supplementary Figures 2, 12, 20 and 22. The HTML has been updated to include a corrected version of the Supplementary Information; the original ...
Chris Eberlein   +7 more
doaj   +1 more source

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