Results 41 to 50 of about 14,444,288 (391)

Linking specification to differentiation:From proneural genes to the regulation of ciliogenesis [PDF]

open access: yes, 2011
Much of developmental biology is concerned with the processes by which cells become committed to particular fates in a regulated fashion, whereas cell biology addresses, among other things, the variety of differentiated forms and functions that cells can
Jarman, Andrew   +2 more
core   +2 more sources

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

open access: yesNature, 2010
The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized that RNAs could possess a regulatory role that relies on their ability to ...
L. Poliseno   +5 more
semanticscholar   +1 more source

Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis

open access: yesScientific Reports, 2021
The Sec61 complex translocates nascent polypeptides into and across the membrane of the endoplasmic reticulum (ER), providing access to the secretory pathway. In this study, we show that Ipomoeassin-F (Ipom-F), a selective inhibitor of protein entry into
Peristera Roboti   +4 more
doaj   +1 more source

Herbal Extract Mixture Modulates Intestinal Antioxidative Capacity and Microbiota in Weaning Piglets

open access: yesFrontiers in Microbiology, 2021
Recently, herbal extracts have been applied in multiple aspects, such as medicine and animal feed. Different compositions of herbal extract mixture (HEM) have various components and diverse functions.
Meiwei Wang   +7 more
doaj   +1 more source

A general introduction to glucocorticoid biology [PDF]

open access: yes, 2019
Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their broad physiological and therapeutic effects, GCs bind to the GC receptor (GR) which belongs to the nuclear receptor ...
Libert, Claude   +2 more
core   +1 more source

Specificity, propagation, and memory of pericentric heterochromatin

open access: yesMolecular Systems Biology, 2014
The cell establishes heritable patterns of active and silenced chromatin via interacting factors that set, remove, and read epigenetic marks. To understand how the underlying networks operate, we have dissected transcriptional silencing in pericentric ...
Katharina Müller‐Ott   +11 more
doaj   +1 more source

Asking Biological Questions of Physical Systems: the Device Approach to Emergent Properties

open access: yes, 2018
Life occurs in concentrated `Ringer Solutions' derived from seawater that Lesser Blum studied for most of his life. As we worked together, Lesser and I realized that the questions asked of those solutions were quite different in biology from those in the
Eisenberg, Bob
core   +1 more source

Development and validation of computational models of cellular interaction [PDF]

open access: yes, 2004
In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L.   +2 more
core   +1 more source

Bubble Lab Exercise [PDF]

open access: yes, 2020
The cell membrane is a ubiquitous component in mammalian cells which control many vital biological functions. It consists of a phospholipid bilayer with embedded protein molecules which serve to transport molecules between the interior and exterior of ...
Beltramo, Peter
core   +1 more source

BIOLOGY AND FUNCTIONS OF NERVE CELLS [PDF]

open access: yesThe Journal OF Nervous and Mental Disease, 1922
n ...
openaire   +2 more sources

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