Results 81 to 90 of about 6,362,947 (287)

Towards a formal semantic model of IEC 61499 function blocks

open access: yes, 2007
This paper proposes a formal model of IEC 61499 function blocks and systems. The model is intended to be used in description of formal semantic model of function blocks, execution.
Vyatkin, Valeriy, Dubinin, Viktor,
core   +1 more source

Concurrent Deterministic Execution Semantics for IEC 61499-Based OT–IT Convergence Industrial Edge Applications

open access: yesIEEE Open Journal of the Industrial Electronics Society
Industrial edge computing provides new possibilities for traditional industrial automation systems. With massive computing, storage, and communication resources equipped with devices on the shop floor, a typical edge device can simultaneously handle ...
Wenbin Dai   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Serotonergic neurons signal reward and punishment on multiple timescales

open access: yeseLife, 2015
Serotonin's function in the brain is unclear. One challenge in testing the numerous hypotheses about serotonin's function has been observing the activity of identified serotonergic neurons in animals engaged in behavioral tasks.
Jeremiah Y Cohen   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Non-Contiguous Protein Recombination [PDF]

open access: yes, 2013
Swapping sequence elements among related proteins can produce chimeric proteins with novel behaviors and improved properties such as enhanced stability. Although homologous mutations are much more conservative than random mutations, chimeras of distantly-
Smith, Matthew Alexander
core   +1 more source

Sparing of number words in oral production

open access: yesFrontiers in Psychology, 2014
Phonological errors seldom affect number words (Bencini et al., 2011). Current views suggest that this effect arises at the post-lexical (buffer) level: the basic phonological building blocks of ordinary words are phonemes, but the building blocks of ...
Carlo Semenza, Francesca Meneghello
doaj   +1 more source

Block sensitivity of minterm-transitive functions

open access: yesTheoretical Computer Science, 2011
Boolean functions with symmetry properties are interesting from a complexity theory perspective; extensive research has shown that these functions, if nonconstant, must have high `complexity' according to various measures. In recent work of this type, Sun gave bounds on the block sensitivity of nonconstant Boolean functions invariant under a transitive
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Synchronous Execution of IEC 61499 Function Blocks Using Esterel

open access: yes, 2007
The IEC 61499 standard proposes a component-oriented approach for specifying industrial-process measurement and control systems using function blocks. Unfortunately, the standard does not provide rigorous semantics for the execution of function blocks ...
Zoran Salcic   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy