Results 71 to 80 of about 6,362,947 (287)
The role of the transcription factor Sox9 for thymic epithelial cell differentation and function [PDF]
, 2011 The thymus provides throughout life the specialized stromal microenvironment required for the lifelong generation of naïve T cells. This vital function is dependent on the regular composition and organization of its microenvironment, where specialized ...
Žalac, Tatjana
core +1 more source
Performance analysis of general purpose and digital signal processor kernels for heterogeneous systems-on-chip [PDF]
Advances in Radio Science, 2003 Various reasons like technology progress, flexibility demands, shortened product cycle time and shortened time to market have brought up the possibility and necessity to integrate different architecture blocks on one heterogeneous System-on-Chip (SoC ...
T. von Sydow, H. Blume, T. G. Noll
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Periodic messages and function blocks scheduling in FF system
, 2001 This paper presents remote periodic messages and Function Blocks (FBs) scheduling in a single segment FF system. Firstly, we regard remote periodic messages and FBs as tasks, and then propose compact mode and only consider precedence constraints to build
Yu HB(于海斌) +3 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
On the number of blocks required to access the core [PDF]
For any transferable utility game in coalitional form with nonempty core, we show that that the number of blocks required to switch from an imputation out of the core to an imputation in the core is less than or equal to n(n-1)/2, where n is the ...
Solal, Philippe +2 more
core
Vertical deformation and tectonic activity in Tianjin area
Geodesy and Geodynamics, 2010 Vertical deformation in Tianjin area during 1992–2008 was calculated from leveling data. The effect of large surface subsidence caused by extensive groundwater pumping was removed by fitting the data along each survey line with a polynomial function. The
Liangqian Guo +6 more
doaj +1 more source
Block sensitivity of weakly symmetric functions
Theoretical Computer Science, 2006 \textit{N. Nisan} [SIAM J. Comput. 20, No. 6, 999--1007 (1991; Zbl 0737.68028)] introduced the concept of block sensitivity of a Boolean function \(f\), denoted by \(\text{bs}(f)\), proved tight bounds for computing \(\text{bs}(f)\) on a CREW PRAM and showed that block sensitivity is polynomially related to many other measures of complexity.
openaire +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source