Results 21 to 30 of about 488,957 (273)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Parameterized inequalities based on three times differentiable functions

Boundary Value Problems
This paper presents a general identity including two real parameters for three times differentiable functions. By using this equality, we prove several inequalities by using diverse function classes such as convex function, bounded function, Lipschitzian
Bouharket Benaissa, Noureddine Azzouz, Hüseyin Budak   +2 more
doaj   +1 more source

Henstock-Kurzweil Integral Transforms

International Journal of Mathematics and Mathematical Sciences, 2012
We show conditions for the existence, continuity, and differentiability of functions defined by , where is a function of bounded variation on with .
Salvador Sánchez-Perales, Francisco J. Mendoza Torres, Juan A. Escamilla Reyna   +2 more
doaj   +1 more source

A universal bound on the variations of bounded convex functions [PDF]

, 2015
Given a convex set $C$ in a real vector space $E$ and two points $x,y\in C$, we investivate which are the possible values for the variation $f(y)-f(x)$, where $f:C\longrightarrow [m,M]$ is a bounded convex function. We then rewrite the bounds in terms of
Kwon, Joon
core  

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Uniformly continuous set-valued composition operators in the space of total φ-bidimensional variation in the sense of Riesz [PDF]

Opuscula Mathematica, 2010
In this paper we prove that if a Nemytskij composition operator, generated by a function of three variables in which the third variable is a function one, maps a suitable large subset of the space of functions of bounded total \(\varphi\)-bidimensional ...
Wadie Aziz, José Giménez, Nelson Merentes, José Luis Sánchez   +3 more
doaj   +1 more source

Myers' type theorem with the Bakry-\'Emery Ricci tensor

, 2018
In this paper we prove a new Myers' type diameter estimate on a complete connected Reimannian manifold which admits a bounded vector field such that the Bakry-\'Emery Ricci tensor has a positive lower bound.
Wu, Jia-Yong
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

On functions of bounded variation [PDF]

Mathematical Proceedings of the Cambridge Philosophical Society, 2016
AbstractThe recently introduced concept of ${\mathcal D}$-variation unifies previous concepts of variation of multivariate functions. In this paper, we give an affirmative answer to the open question from [20] whether every function of bounded Hardy–Krause variation is Borel measurable and has bounded ${\mathcal D}$-variation.
Aistleitner, Christoph, Pausinger, Florian, Svane, Anne Marie, Tichy, Robert   +3 more
openaire   +3 more sources