Results 31 to 40 of about 43,776 (261)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
In this paper we introduce the notion of “function of second bounded variation” in the sense of Shiba, and we show that if a superposition operator applies the space of all such functions on itself and it is uniformly bounded, then its generating ...
José Giménez +3 more
doaj +2 more sources
We introduce a function space with some generalization of bounded variation in the sense of de la Vallée Poussin and study some of its properties, like embeddings and decompositions, among others.
René Erlín Castillo +2 more
doaj +1 more source
We prove that if a superposition operator maps a subset of the space of all metric-vector-space-valued-functions of bounded n-dimensional Φ-variation into another such space, and is uniformly continuous, then the generating function of the operator is an
Bracamonte Mireya +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modeling and Optimizing the System Reliability Using Bounded Geometric Programming Approach
The geometric programming problem (GPP) is a beneficial mathematical programming problem for modeling and optimizing nonlinear optimization problems in various engineering fields.
Shafiq Ahmad +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The expected variation of random bounded integer sequences of finite length
From the enumerative generating function of an abstract adjacency statistic, we deduce the mean and variance of the variation on random permutations, rearrangements, compositions, and bounded integer sequences of finite length.
Rudolfo Angeles +3 more
doaj +1 more source
Transformation operators for impedance Sturm–Liouville operators on the line
In the Hilbert space $H:=L_2(\mathbb{R})$, we consider the impedance Sturm--Liouville operator $T:H\to H$ generated by the differential expression $ -p\frac{d}{dx}{\frac1{p^2}}\frac{d}{dx}p$, where the function $p:\mathbb{R}\to\mathbb{R}_+$ is of ...
M. Kazanivskiy +2 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

