Results 61 to 70 of about 43,776 (261)
Journal of Inequalities and ApplicationsThis paper develops weighted Euler–Maclaurin-type inequalities using Riemann–Liouville fractional integrals for classes of differentiable convex functions and functions of bounded variation.
Areej A. Almoneef +3 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Measure integral inclusions with fast oscillating data
Electronic Journal of Differential Equations, 2015 We prove the existence of regulated or bounded variation solutions, via a nonlinear alternative of Leray-Schauder type, for the measure integral inclusion $$ x(t) \in \int_0^t F(s, x(s)) \,du(s), $$ under the assumptions of regularity, respectively
Bianca-Renata Satco
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Countable Additivity of Spreading the Differentiation Operator
Моделирование и анализ информационных систем, 2014 In this article, we continue the study of the properties acquired by the differentiation operator Λ with spreading beyond the space W1¹. The study is conducted by introducing the family of spaces Yp¹ , 0 < p < 1, having analogy with the family Wp¹,
A. N. Morozov
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Boundedness of higher-order Marcinkiewicz-Type integrals
International Journal of Mathematics and Mathematical Sciences, 2006 Let A be a function with derivatives of order m and DγA∈Λ˙β ...
Shanzhen Lu, Huixia Mo
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
On Functions of Bounded (p,k)-Variation
Journal of Function Spaces and Applications, 2012 We introduce and study the concept of (p,k)-variation ...
N. Merentes, S. Rivas, J. L. Sanchez
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