Results 101 to 110 of about 2,857,572 (312)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Linear systems and determinantal random point fields. [PDF]

open access: yes, 2008
Tracy and Widom showed that fundamentally important kernels in random matrix theory arise from systems of differential equations with rational coefficient.
Blower, Gordon
core   +1 more source

Análise de pontos por função fuzzy: modelo e resultados.

open access: yesRevista Tecnologia, 2009
Function Point Analysis(FPA) is a largely used techniqueto estimate the size of development project, enhancemen ptroject or applications already installed.
Osias Souza Lima Júnior   +2 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Reference Point Formation Over Time: A Weighting Function Approach [PDF]

open access: yes
Although the concept of reference point dependent preferences has been adopted to almost all fields of behavioral economics, especially marketing and behavioral finance, we still know very little about how decision makers form their reference points ...
Baucells, Manel   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Function point analysis methods research.

open access: yes, 2011
To effectively manage software development we must be able to measure software. Alan Albrecht in IBM Corporation in 1979 proposed the use of function point analysis method.
Gervė, Šarūnas,
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Note on changing-point testing for nonparametric regression function

open access: yes, 2010
Nonparametric regression analysis is an important and popular method to investigate the regression model of the source of data. Traditionally, regression analysis is often used under the assumption that the regression function is continuous and smooth ...
伍志祥; Wu, Jyh-shyang; Lai, Yao-tsung
core  

Study on Spatial Scale Selection Problem: Taking Port Spatial Expression as Example

open access: yesJournal of Marine Science and Engineering
Spatial scale is a key factor, which affects the accuracy of spatial expression and further influences the spatial planning of a research area. In order to help improve the efficiency and accuracy of optimal scale selection for all sizes of research ...
Yunzhuo Xu   +3 more
doaj   +1 more source

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