Results 131 to 140 of about 2,857,572 (312)

Multi-dimensional Point Process Models in R

open access: yes
A software package for fitting and assessing multidimensional point process models using the R statistical computing environment is described. Methods of residual analysis based on random thinning are discussed and implemented.
Roger Peng
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The use of function points to find cost analogies

open access: yes, 1994
Finding effective techniques for the early estimation of project effort remains an important — and frustratingly elusive — research objective for the software development community.
Atkinson, K, Shepperd, M J
core  

Existence and Uniqueness of a Fixed Point for the Bellman Operator in Deterministic Dynamic Programming [PDF]

open access: yes
We study existence and uniqueness of a fixed point for the Bellman operator in deterministic dynamic programming. Without any topological assumption, we show that the Bellman operator has a unique fixed point in a restricted domain, that this fixed point
Takashi Kamihigashi
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Approche variationnelle de la fonction rang : relaxation convexe, sous-différentiation généralisée, régularisation-approximation de Moreau

open access: yes, 2013
Dans ce mémoire de these, nous étudions la fonction rang du point de vue variationnel. La raison pour laquelle nous nous intéressons à cette fonction est qu'elle apparaît comme une fonction objectif (ou comme fonction contrainte) dans divers problèmes d ...
Le, Hai Yen
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

bcp: An R Package for Performing a Bayesian Analysis of Change Point Problems

open access: yes
Barry and Hartigan (1993) propose a Bayesian analysis for change point problems. We provide a brief summary of selected work on change point problems, both preceding and following Barry and Hartigan.
Chandra Erdman, John W. Emerson
core  

Sufficient Conditions for Optimal Stability in Hilfer–Hadamard Fractional Differential Equations

open access: yesMathematics
The primary objective of this study is to explore sufficient conditions for the existence, uniqueness, and optimal stability of positive solutions to a finite system of Hilfer–Hadamard fractional differential equations with two-point boundary conditions.
Safoura Rezaei Aderyani   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy