Results 51 to 60 of about 1,559,492 (313)

On the semicontinuity of functionals on function spaces

open access: yesProceedings of the American Mathematical Society
Results on the upper and lower semicontinuity of functionals defined on spaces of convex and more general functions are established. In particular, the following result is obtained. Let $ϕ(v; \cdot)$ be the density of the absolutely continuous part of a Radon measure $Φ(v; \cdot)$ associated to a function $v\colon X\rightarrow \mathbb{R}$ defined on ...
Baêta, Fernanda M., Ludwig, Monika
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A function space from a compact metrizable space to a dendrite with the hypo-graph topology

open access: yesOpen Mathematics, 2015
Let X be an infinite compact metrizable space having only a finite number of isolated points and Y be a non-degenerate dendrite with a distinguished end point v.
Yang Hanbiao   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An Ontological Interpretation of the Wave Function [PDF]

open access: yes, 2013
It is argued that, based on a new analysis of two-body systems, wave function realism seems to imply an unique ontological interpretation of the wave function, according to which the wave function represents the state of random discontinuous motion of ...
Gao, Shan, Shan Gao
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Wave Function and Its Evolution [PDF]

open access: yes, 2011
The meaning of the wave function and its evolution are investigated. First, we argue that the wave function in quantum mechanics is a description of random discontinuous motion of particles, and the modulus square of the wave function gives the ...
Gao, Shan, Shan Gao
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Clustering dichotomously scored items through functional k-means algorithm

open access: yes, 2016
In the educational field, it is common to analyze the probability of a correct response to a test item as a continuous function of the item parameters and the subject ability. This relation is given by the item response function.
Di Battista, Tonio; Dipartimento di Metodi Quantitativi e Teoria Economica, Università "G. d'Annunzio" Chieti-Pescara   +1 more
core   +1 more source

ON A FUNCTION OF HYPERCONNECTED SPACES

open access: yesDemonstratio Mathematica, 2007
In this paper, we introduce a new class of functions called contra R-maps which is contained in the class of regular set connected functions and contains (?, s)-continuous functions. Some characterizations of hyperconnected spaces are given by using contra R-maps and we observe that hyperconnectedness is preserved under the contra R-maps.
openaire   +3 more sources

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