Results 51 to 60 of about 10,585,569 (293)

A function space from a compact metrizable space to a dendrite with the hypo-graph topology

open access: yesOpen Mathematics, 2015
Let X be an infinite compact metrizable space having only a finite number of isolated points and Y be a non-degenerate dendrite with a distinguished end point v.
Yang Hanbiao   +2 more
doaj   +1 more source

Comparison between traditional and predictive methods in Prediction of post treatment mandibular arch [PDF]

open access: yesIranian Journal of Orthodontics, 2012
Background and aim: The aim of present study was to predict post treatment space available of mandibular arch and compare this method of measurement with the previous methods.
Ahmad Sodagar   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A function space model for canonical systems [PDF]

open access: yes, 2011
Recently, a generalization to the Pontryagin space setting of the notion of canonical (Hamiltonian) systems which involves a finite number of inner singularities has been given.
Woracek, H., Langer, Matthias
core   +3 more sources

Turbo Equalization of Convolutional Coded and Concatenated Space Time Trellis Coded Systems using Radial Basis Function Aided Equalizers

open access: yes, 2001
In this contribution a reduced-complexity radial basis function (RBF) aided neural-network based turbo equalization (TEQ) scheme is proposed for employment in a serially concatenated convolutional coded and systematic space time trellis coded (CC-SSTTC ...
Yeap, B.L., Yee, M.S., Hanzo, L.
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

ON A FUNCTION OF HYPERCONNECTED SPACES

open access: yesDemonstratio Mathematica, 2007
In this paper, we introduce a new class of functions called contra R-maps which is contained in the class of regular set connected functions and contains (?, s)-continuous functions. Some characterizations of hyperconnected spaces are given by using contra R-maps and we observe that hyperconnectedness is preserved under the contra R-maps.
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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