Results 61 to 70 of about 10,585,569 (293)
Changing weekend effects of air pollutants in Beijing under 2020 COVID-19 lockdown controls
npj Urban Sustainability, 2022 In 2020, lockdown control measures were implemented to prevent a novel coronavirus disease 19 (COVID-19) pandemic in many places of the world, which largely reduced human activities.
Lingyun Wu, Junfei Xie, Keyu Kang
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2007 This contribution considers nonlinear space-time equalisation (STE) designed for single-input multiple-output (SIMO) systems. By exploiting the inherent symmetry of the underlying optimal Bayesian STE solution, a novel symmetric radial basis function ...
Liu, S., Hanzo, L., Chen, S.
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
On Compactness in Function Spaces [PDF]
Proceedings of the American Mathematical Society, 1972 There are shown some implications from pseudocompactness to compactness or sequential compactness. The latter, sequential compactness, is obtained via metrization.
openaire +3 more sources
A Decomposition of the Dual Space of Some Banach Function Spaces [PDF]
, 2012 We give a decomposition for the dual space of some Banach Function Spaces as the Zygmund space EXP of the exponential integrable functions, the Marcinkiewicz space ,∞, and the Grand Lebesgue Space ),
FORMICA, MARIA ROSARIA +3 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source