Results 101 to 110 of about 7,650,207 (262)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Functional barriers: Properties and evaluation

, 2005
Functional barriers are multilayer structures deemed to prevent migration of some chemicals released by food-contact materials into food. In the area of plastics packaging, different migration behaviours of mono- and multilayer structures are assessed in
Pennarun, Pierre-Yves, Saillard, P, Vidal, Laure, Aucejo, S., Dainelli, D, Papaspyrides, Costas, Dole, Patrice, Cruz Garcia, C. de la, N'Gono, Yvette, De la Cruz Garcia, C, Dole, P, Pennarun, PY, Aucejo, Susana, Hankemeier, Thomas, Vitrac, Olivier, Voulzatis, Yiannis, Saillard, P., Hankemeier, T., Pastorelli, Sara, Saillard, Philippe, Paseiro, P, Pennarun, P.Y., Paseiro, Perfecto, Voulzatis, Y, Feigenbaum, A, Dole, P., Vidal, L., Papaspyrides, CD, Pavlidou, S., Papaspyrides, C.D., Pavlidou, S, N'Gono, Y, Dainelli, Dario, Aucejo, S, Vitrac, O, N'Gono, Y., Paseiro, P., Voulzatis, Y., de La Cruz-Garcia, Carlos, Hankemeier, T, Pavlidou, Silvia, Dainelli, D., Feigenbaum, Alexandre, Pastorelli, S., Pastorelli, S, Vidal, L, Feigenbaum, A., Vitrac, O.   +47 more
core   +1 more source

Model of Efficiency Assessment of Regulation In The Banking Seсtor

Vestnik MGIMO-Universiteta, 2014
In this article, the modern system of regulation of the national banking sector is viewed, which, according to the author, needs theoretical judgment, structuring, disclosure of the maintenance of efficiency of functioning is considered.
Irina V. Larionova
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Functional Analysis in Interdisciplinary Applications

, 2017
This volume presents current research in functional analysis and its applications to a variety of problems in mathematics and mathematical physics. The book contains over forty carefully refereed contributions to the conference “Functional Analysis in ...
Sadybekov, Makhmud, Kal'menov, Tynysbek Sh., Sadybekov, Makhmud A.editor, Kalmenov, Tynysbek, Nursultanov, Erlan, Ruzhansky, MichaeleditorWE168020029013460000-0001-8633-55708B63EA9E-C5C8-11E8-8987-A2685607D3EF, Nursultanov, Erlan D., Kal'menov, Tynysbek Sh.editor, Ruzhansky, Michael, Sadybekov, Makhmud A., Nursultanov, Erlan D.editor   +10 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Technological process modes determination for surface formation of substrates for functional components of microoptoelectromechanical systems

, 2021
A method of technological modes determining for the process of substrates surfaces shaping for the functional components of microoptoelectromechanical systems is proposed, which allows to improve the quality of the substrates.
Botsman, I., Chala, O., Nevliudov, I.
core