Results 111 to 120 of about 7,650,207 (262)

Acknowledgement to Reviewers of Journal of Functional Morphology and Kinesiology in 2019

open access: yesJournal of Functional Morphology and Kinesiology, 2020
Journal Of Functional Morphology And Kinesiology Editorial
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Assessment of functional status and quality of life of students after acute respiratory viral diseases

open access: yesPedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2015
Purpose : explore the functional status and quality of life of students after acute viral infectious diseases. Material : a total of 25 students aged 19-22 years after the acute respiratory viral infections and 20 healthy people.
I.Ya. Hnyp
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Neuroplastic changes in resting-state functional connectivity after stroke rehabilitation

open access: yes, 2017
Most neuroimaging research in stroke rehabilitation mainly focuses on the neural mechanisms underlying the natural history of post-stroke recovery. However, connectivity mapping from resting-state fMRI is well suited for different neurological conditions
Fan, Yang-teng; Wu, Ching-yi; Liu, Ho-ling; Lin, Keh-chung; Wai, Yau-yau; Chen, Yao-liang
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Dynamics of development motive capabilities, psychophysiological and functional possibilities of boys 4-6 years [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
The problem of determination of level of development motive capabilities is examined. Directions of prognostication inclination of children of early age are rotined to the certain type of motive activity.
Gavrishko S.G.
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Comparing Fermented Food and Vitamin E on Exercise-mediated Nrf2/ARE Activation in Middle-aged/ Elderly: A Randomized, Double-blind Clinical Study

open access: yes
Background: There is a compelling need to emphasize the importance of deepening the rationale behind functional foods research in molecular biology. Indeed, establishing stringent criteria to evaluate functional food interventions in disease prevention ...
Cervi, Joseph   +9 more
core   +1 more source

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