Results 91 to 100 of about 12,441,098 (355)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Outcomes of lacrimal gland injection of botulinum toxin in functional versus nonfunctional epiphora
Oman Journal of Ophthalmology, 2019 PURPOSE: The purpose of this study is to assess the outcomes of lacrimal gland injections of botulinum toxin A (BoNTA) for epiphora secondary to lacrimal drainage disorders and functional epiphora.
Swati Singh +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Microbiology, 2017 Understanding microbial communities in terms of taxon and function is essential to decipher the biogeochemical cycling in aquatic ecosystems. Lakes and their input streams are highly linked.
Ze Ren +9 more
doaj +1 more source
HEUN FUNCTIONS VERSUS ELLIPTIC FUNCTIONS [PDF]
Difference Equations, Special Functions and Orthogonal Polynomials, 2007 Communication at the International Conference on Difference Equations, Special Functions and Applications, Munich, 25-30 july 2005, latex 2e, 20 ...
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
eLifeInterpretation of variants identified during genetic testing is a significant clinical challenge. In this study, we developed a high-throughput CDKN2A functional assay and characterized all possible human CDKN2A missense variants.
Hirokazu Kimura +3 more
doaj +1 more source
Orbital cellulitis in a neonate of the tooth bud origin : A case report
Indian Journal of Ophthalmology, 2014 Orbital cellulitis is a serious, yet uncommon infection in neonates. It can result in significant sight and life threatening complications. Most commonly, it occurs secondarily as the result of a spread of infection from the sinuses.
Poonam Lavaju +3 more
doaj +1 more source
Synthesizing Functional Reactive Programs [PDF]
, 2019 Functional Reactive Programming (FRP) is a paradigm that has simplified the construction of reactive programs. There are many libraries that implement incarnations of FRP, using abstractions such as Applicative, Monads, and Arrows.
Finkbeiner, Bernd +3 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source