Results 161 to 170 of about 11,568 (285)

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, EarlyView.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Enhanced purification coupled with biophysical analyses shows cross-β structure as a core building block for Streptococcus mutans functional amyloids. [PDF]

Sci Rep, 2020
Barran-Berdon AL, Ocampo S, Haider M, Morales-Aparicio J, Ottenberg G, Kendall A, Yarmola E, Mishra S, Long JR, Hagen SJ, Stubbs G, Brady LJ.   +11 more
europepmc   +1 more source

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

Arthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G.B. Grashof, Laurie Vaillant, Renske J.H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, ImmunAID consortium, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +17 more
wiley   +1 more source

Dynamic visualization of extracellular matrix components in <i>S. aureus</i> colony biofilms reveals functional amyloids leading to the formation of cap-like structures. [PDF]

Biofilm
Zhang T, Bär J, Risberg L, Gómez Mejia A, Hammar H, Löffler S, Otzen DE, Andreasen M, Meyer RL, Melican K, Zinkernagel AS, Richter-Dahlfors A.   +11 more
europepmc   +1 more source

Functional amyloids promote retention of public goods in bacteria. [PDF]

Proc Biol Sci, 2019
Bruce JB, West SA, Griffin AS.
europepmc   +1 more source

Functional bacterial amyloid nanomaterials

, 2016
Cataloged from PDF version of article. Thesis (M.S.): Bilkent University, Department of Materials Science and Nanotechnology, İhsan Doğramacı Bilkent University, 2016. Includes bibliographical references (leaves 91-109). Mis-folded or unfolded proteins tend to aggregate and aggregated structures are called as amyloids.
openaire   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Microbial amyloids as functional biomaterials

, 2021
Cataloged from PDF version of article. Thesis (Ph.D.): Bilkent University, Department of Materials Science and Nanotechnology, İhsan Doğramacı Bilkent University, 2021. Includes bibliographical references (leaves 138-149). Amyloids are fibrillar aggregations of proteins, dominated by β-sheets in the structure.
openaire   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Ecology and Biogenesis of Functional Amyloids in Pseudomonas. [PDF]

J Mol Biol, 2018
Rouse SL, Matthews SJ, Dueholm MS.
europepmc   +1 more source