Results 251 to 260 of about 11,568 (285)
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Functional amyloid materials at surfaces/interfaces
Biomaterials Science, 2018With the development of nanotechnology, functional amyloid materials at surfaces/interfaces are drawing increasing attention, and numerous remarkable applications are emerging, which are outlined in this reivew.
Chen Li +4 more
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Surface effects on functional amyloid formation
NanoscaleFibril nucleation during protein aggregation is a heterogeneous process highly dependent on the surfaces present during the process.
Alexander J. Dear +9 more
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Supramolecular photochirogenesis with functional amyloid superstructures
Chemical Communications, 2013Chiral variants of amyloid fibrils prepared by agitating acidified solutions of bovine insulin at 45 °C not only induced quasi-mirror-imaged circular dichroism spectra upon complexation with 2-anthracenecarboxylate but also gave anti-head-to-head-cyclodimers of the opposite absolute configurations upon photoirradiation.
Masaki Nishijima +7 more
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Protein Misfolding, Functional Amyloid, and Human Disease
Annual Review of Biochemistry, 2006Peptides or proteins convert under some conditions from their soluble forms into highly ordered fibrillar aggregates. Such transitions can give rise to pathological conditions ranging from neurodegenerative disorders to systemic amyloidoses. In this review, we identify the diseases known to be associated with formation of fibrillar aggregates and the ...
CHITI, FABRIZIO, C. M. DOBSON
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Not just amyloid: physiological functions of the amyloid precursor protein family
Nature Reviews Neuroscience, 2017Amyloid precursor protein (APP) gives rise to the amyloid-β peptide and thus has a key role in the pathogenesis of Alzheimer disease. By contrast, the physiological functions of APP and the closely related APP-like proteins (APLPs) remain less well understood.
Ulrike C, Müller +2 more
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Functional amyloid aggregation
2010Protein amyloid aggregation is generally considered undesirable and harmful. Anyway, this is not always true. This book covers the most relevant examples of functional amyloid aggregation, from microbes to man.
RIGACCI, STEFANIA, BUCCIANTINI, MONICA
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Functional precision oncology using patient-derived assays: bridging genotype and phenotype
Nature Reviews Clinical Oncology, 2023Emile E Voest
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In vivo functional screening for systems-level integrative cancer genomics
Nature Reviews Cancer, 2020Julia Weber +2 more
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