Results 91 to 100 of about 7,583,872 (228)

Thrombomodulin is a stronger indicator of combined oral contraceptives-induced activated protein C pathway resistance in the thrombin generation test than activated protein C

open access: yesFrontiers in Cardiovascular Medicine
BackgroundThe mechanism by which combined oral contraceptives (COCs) lead to hypercoagulation is not fully understood, although activated protein C (APC) pathway resistance has been implicated.
Marisa Ninivaggi   +6 more
doaj   +1 more source

New Azaphilones from Nigrospora oryzae Co-Cultured with Beauveria bassiana

open access: yesMolecules, 2018
In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana, the endophytes in the seeds of Dendrobium officinale, were examined for metabolite diversity.
Zhuo-Xi Zhang   +7 more
doaj   +1 more source

Protein kinase FAM20C—when subcellular localization matters

open access: yesFEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

Analysis of Adjoint Error Correction for Superconvergent Functional Estimates [PDF]

open access: yes, 2001
Earlier work introduced the notion of adjoint error correction for obtaining superconvergent estimates of functional outputs from approximate PDE solutions. This idea is based on a posteriori error analysis suggesting that the leading order error term in
Giles, M. B., Pierce, Niles A.
core  

Transcription factor TFE3 enhances cell cycle and cancer progression by binding to the hTERT promoter

open access: yesCancer Communications, 2021
Beiping Miao   +6 more
doaj   +1 more source

Potentiality of plants as source of insecticide principles

open access: yesJournal of Saudi Chemical Society, 2014
In the search for alternatives to conventional insecticides, essential oils extracted from aromatic plants have been widely investigated. Their toxicities toward insects were of special interest during the last decade.
Safia Zoubiri, Aoumeur Baaliouamer
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Stimulation-induced cytokine polyfunctionality as a dynamic concept

open access: yeseLife
Cytokine polyfunctionality is a well-established concept in immune cells, especially T cells, and their ability to concurrently produce multiple cytokines has been associated with better immunological disease control and subsequent effectiveness during ...
Kevin Portmann, Aline Linder, Klaus Eyer
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

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