Results 61 to 70 of about 7,524,603 (346)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

An integrated experimental and analytical approach for the analysis of the mechanical interaction between metal porous scaffolds and bone: implications for stress shielding in orthopedic implants

Frontiers in Bioengineering and Biotechnology
IntroductionMetal porous structures are becoming a standard design feature of orthopedic implants such as joint endoprostheses. The benefits of the pores are twofold: 1) help improve the cementless primary stabilization of the implant by increasing ...
Roberto Ramaglia Amadasi, Giulia Rogati, Erica Liverani, Alberto Leardini, Paolo Caravaggi   +4 more
doaj   +1 more source

Boolean-Valued Set-Theoretic Systems: General Formalism and Basic Technique

Mathematics, 2021
This article is devoted to the study of the Boolean-valued universe as an algebraic system. We start with the logical backgrounds of the notion and present the formalism of extending the syntax of Boolean truth values by the use of definable symbols ...
Alexander Gutman
doaj   +1 more source

Functional Data Analysis [PDF]

Annual Review of Statistics and Its Application, 2016
With the advance of modern technology, more and more data are being recorded continuously during a time interval or intermittently at several discrete time points. These are both examples of functional data, which has become a commonly encountered type of data.
Wang, Jane-Ling, Chiou, Jeng-Min, Müller, Hans-Georg   +2 more
openaire   +3 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Genetic Regulation of Liver Metabolites and Transcripts Linking to Biochemical-Clinical Parameters

Frontiers in Genetics, 2019
Given the central metabolic role of the liver, hepatic metabolites and transcripts reflect the organismal physiological state. Biochemical-clinical plasma biomarkers, hepatic metabolites, transcripts, and single nucleotide polymorphism (SNP) genotypes of
Siriluck Ponsuksili, Nares Trakooljul, Frieder Hadlich, Karen Methling, Michael Lalk, Eduard Murani, Klaus Wimmers, Klaus Wimmers   +7 more
doaj   +1 more source

Ethnoarchaeology and Functional Analysis

, 2014
Ethnoarchaeology and ethnoanalogical sources as a whole are crucial for the generation of interpretations in prehistory in general, and particularly in lithic functional analysis. These sources inform about the use of certain tools, operative chains and full technical processes, or about the different contexts in which production is carried out.
González Urquijo, Jesús E., Beyries, Sylvie, Ibáñez-Estévez, Juan José   +2 more
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

MicroRNAs in blood act as biomarkers of colorectal cancer and indicate potential therapeutic targets

Molecular Oncology, 2021
Association studies have linked alterations of blood‐derived microRNAs (miRNAs) with colorectal cancer (CRC). Here, we performed a microarray‐based comparison of the profiles of 2549 miRNAs in 80 blood samples from healthy donors and patients with ...
Axel Stang, Hauke Weilert, Michael J. Lipp, Karl J. Oldhafer, Jörg D. Hoheisel, Chaoyang Zhang, Andrea S. Bauer   +6 more
doaj   +1 more source

ROI-Based Analysis of Functional Imaging Data [PDF]

, 2002
In this technical report, we present fMRI analysis techniques that test functional hypotheses at the region of interest (ROI) level. An SPM-compatible Matlab toolbox has been developed which allows the creation of subject-specific ROI masks based on ...
Ghosh, Satrajit, Guenther, Frank, Nieto-Castanon, Alfonso, Tourville, Jason   +3 more
core   +1 more source