Results 61 to 70 of about 33,941,795 (386)

Functional principal components analysis via penalized rank one approximation [PDF]

, 2008
Two existing approaches to functional principal components analysis (FPCA) are due to Rice and Silverman (1991) and Silverman (1996), both based on maximizing variance but introducing penalization in different ways.
Buja, Andreas, Huang, Jianhua Z., Shen, Haipeng   +2 more
core   +5 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

In situ, Cell-free Protein Expression on Microarrays and Their Use for the Detection of Immune Responses

Bio-Protocol, 2019
Until recently, whole-proteome microarrays for comprehensive studies of protein interactions were mostly produced by individual cloning and cellular expression of very many open reading frames, followed by protein isolation and purification as well as ...
Katrin Hufnagel, Dennis Reininger, Siu Ng, Nadine Gassert, Juliane Rohland, Soroosh Shahryarhesami, Andrea Bauer, Tim Waterboer, Jörg Hoheisel   +8 more
doaj   +1 more source

N-Acetylcysteine Regenerates In Vivo Mercaptoalbumin

Antioxidants, 2022
Human serum albumin (HSA) represents the most abundant plasma protein, with relevant antioxidant activity due to the presence of the sulfhydryl group on cysteine at position 34 (Cys34), the latter being one of the major target sites for redox-dependent ...
Alessandra Anna Altomare, Maura Brioschi, Sonia Eligini, Alice Bonomi, Beatrice Zoanni, Ada Iezzi, Costantino Jemos, Benedetta Porro, Yuri D’Alessandra, Anna Guarino, Emanuela Omodeo Salè, Giancarlo Aldini, Piergiuseppe Agostoni, Cristina Banfi   +13 more
doaj   +1 more source

Functional factor analysis for periodic remote sensing data [PDF]

, 2012
We present a new approach to factor rotation for functional data. This is achieved by rotating the functional principal components toward a predefined space of periodic functions designed to decompose the total variation into components that are nearly ...
Friedl, Mark, Hooker, Giles, Liu, Chong, Ray, Surajit   +3 more
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A consensus protocol for functional connectivity analysis in the rat brain [PDF]

, 2023
Joanes Grandjean, Gabriel Desrosiers-Grégoire, Cynthia Anckaerts, Diego Ángeles-Valdéz, Fadi Ayad, David André Barrière, Ines Blockx, Aleksandra Bortel, Margaret Broadwater, Beatriz M Cardoso, Marina Célestine, Jorge E. Chavez-Negrete, Sangcheon Choi, Emma Christiaen, Perrin Clavijo, Luis M. Colón-Pérez, Samuel Cramer, Tolomeo Daniele, Elaine Dempsey, Yujian Diao, Arno Doelemeyer, David Dopfel, Lenka Dvořáková, Claudia Falfán-Melgoza, Francisca F. Fernandes, Caitlin Fowler, Antonio Fuentes-Ibañez, Clément M. Garin, Eveline Gelderman, Carla E. M. Golden, Chao Guo, Marloes J. A. G. Henckens, Lauren A. Hennessy, Péter Hermán, Nita Hofwijks, Corey Horien, Tudor M. Ionescu, Jolyon A. Jones, Johannes Kaesser, Eugene Kim, Henriette Lambers, Alberto Lazari, Sung-Ho Lee, Amanda Lillywhite, Yikang Liu, Yanyan Y. Liu, Alejandra López-Castro, Xavier López-Gil, Zilu Ma, Eilidh MacNicol, Dan Madularu, Francesca Mandino, Sabina Marciano, Matthew J. McAuslan, Patrick McCunn, Alison McIntosh, Xianzong Meng, Lisa Meyer-Baese, Stephan Missault, Federico Moro, Daphne M. P. Naessens, Laura J. Nava-Gomez, Hiroi Nonaka, Juan José Ortiz, Jaakko Paasonen, Lore M. Peeters, Mickaël Pereira, Pablo D. Pérez, Marjory Pompilus, M. J. W. Prior, Rustam Rakhmatullin, Henning M. Reimann, Jonathan Reinwald, Rodrigo Triana Del Rio, Alejandro Rivera-Olvera, Daniel Ruiz-Pérez, Gabriele Russo, Tobias J. Rutten, Rie Ryoke, Markus Sack, Piergiorgio Salvan, Basavaraju G. Sanganahalli, Aileen Schroeter, Bhedita J. Seewoo, Erwan Selingue, Aline Seuwen, Bowen Shi, Nikoloz Sirmpilatze, Joanna A. B. Smith, Corrie Smith, Filip Sobczak, Petteri Stenroos, Milou Straathof, Sandra Strobelt, Akira Sumiyoshi, Kengo Takahashi, Maria E. Torres-García, Raúl Tudela, Monica van den Berg, Kajo van der Marel   +99 more
openalex   +1 more source

Analysis of Brownian functionals [PDF]

, 1976
We discuss functionals of Brownian motion by expressing them as those of white noise. We then proceed to generalize them to obtain generalized functionals of Brownian motion. Throughout this paper the integral representation of those functionals is a powerful tool.
openaire   +1 more source

Functional principal component analysis of spatially correlated data [PDF]

, 2016
This paper focuses on the analysis of spatially correlated functional data. We propose a parametric model for spatial correlation and the between-curve correlation is modeled by correlating functional principal component scores of the functional data ...
Hooker, Giles, Liu, Chong, Ray, Surajit
core   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source