Results 111 to 120 of about 557,186 (345)

Functional annotation of genomic sequences of Hevea brasiliensis [PDF]

open access: yes, 2013
The rubber tree (Hevea brasiliensis) is a recent domesticated endemic tree species from Amazonian rain forest. It is an important crop to rubber industries due the latex producing, which has better quality compared to the synthetic rubber.
Cardoso-Silva, Claudio Benicio   +8 more
core  

PANNOTATOR:an automated tool for annotation of pan-genomes [PDF]

open access: yes, 2013
Due to next-generation sequence technologies, sequencing of bacterial genomes is no longer one of the main bottlenecks in bacterial research and the number of new genomes deposited in public databases continues to increase at an accelerating rate.
Abdelzaher, A   +14 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Development of FuGO: An ontology for functional genomics investigations [PDF]

open access: yes, 2006
The development of the Functional Genomics Investigation Ontology (FuGO) is a collaborative, international effort that will provide a resource for annotating functional genomics investigations, including the study design, protocols and instrumentation ...
Brinkman, Ryan R.   +10 more
core  

SIFTER search: a web server for accurate phylogeny-based protein function prediction. [PDF]

open access: yes, 2015
We are awash in proteins discovered through high-throughput sequencing projects. As only a minuscule fraction of these have been experimentally characterized, computational methods are widely used for automated annotation.
Brenner, Steven E   +2 more
core   +5 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Function failure annotation

open access: yes, 2019
We have been seeing an evolution in proposals for the best syntax for describing how to mark how a function fails, such that compilers and linkers can much better optimise function calls than at present. These papers were spurred by [WG21 P0709] Zero-overhead deterministic exceptions, which proposes deterministic exception handling for C++, whose ...
Douglas, Niall, Gustedt, Jens
openaire   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks

open access: yesBMC Bioinformatics, 2007
Background Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data mining and processing tools.
Mazo Ilya   +4 more
doaj   +1 more source

Evaluating automatically acquired f-structures against PropBank [PDF]

open access: yes, 2005
An automatic method for annotating the Penn-II Treebank (Marcus et al., 1994) with high-level Lexical Functional Grammar (Kaplan and Bresnan, 1982; Bresnan, 2001; Dalrymple, 2001) f-structure representations is presented by Burke et al. (2004b).
Burke, Michael   +3 more
core  

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