Results 121 to 130 of about 361,695 (297)

Treebank-based acquisition of wide-coverage, probabilistic LFG resources: project overview, results and evaluation [PDF]

open access: yes, 2004
This paper presents an overview of a project to acquire wide-coverage, probabilistic Lexical-Functional Grammar (LFG) resources from treebanks. Our approach is based on an automatic annotation algorithm that annotates “raw” treebank trees with LFG f ...
O'Donovan, Ruth   +5 more
core  

Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans [PDF]

open access: yes, 2011
The genomes of numerous parasitic nematodes are currently being sequenced, but their complexity and size, together with high levels of intra-specific sequence variation and a lack of reference genomes, makes their assembly and annotation a challenging ...
Gilleard John S.   +34 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks

open access: yesBMC Bioinformatics, 2007
Background Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data mining and processing tools.
Mazo Ilya   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

DCU 250 Arabic dependency bank: an LFG gold standard resource for the Arabic Penn treebank [PDF]

open access: yes, 2006
This paper describes the construction of a dependency bank gold standard for Arabic, DCU 250 Arabic Dependency Bank (DCU 250), based on the Arabic Penn Treebank Corpus (ATB) (Bies and Maamouri, 2003; Maamouri and Bies, 2004) within the theoretical ...
Dichy, J.   +3 more
core  

Arabidopsis halleri functional annotation

open access: yes, 2016
Functional annotation for Arabidopsis halleri ssp. gemmifera Tada mine.
Shimizu-Inatsugi, Rie   +13 more
core   +1 more source

Next-Generation High-Throughput Functional Annotation of Microbial Genomes

open access: yesmBio, 2016
Host infection by microbial pathogens cues global changes in microbial and host cell biology that facilitate microbial replication and disease. The complete maps of thousands of bacterial and viral genomes have recently been defined; however, the rate at
Ralph S. Baric   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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