Results 141 to 150 of about 557,186 (345)

Automatic annotation of the Penn-treebank with LFG f-structure information [PDF]

open access: yes, 2002
Lexical-Functional Grammar f-structures are abstract syntactic representations approximating basic predicate-argument structure. Treebanks annotated with f-structure information are required as training resources for stochastic versions of unification ...
Andy Way   +4 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Evaluation of an automatic f-structure annotation algorithm against the PARC 700 dependency bank [PDF]

open access: yes, 2004
An automatic method for annotating the Penn-II Treebank (Marcus et al., 1994) with high-level Lexical Functional Grammar (Kaplan and Bresnan, 1982; Bresnan, 2001; Dalrymple, 2001) f-structure representations is described in (Cahill et al., 2002; Cahill ...
Burke, Michael   +4 more
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Preparing, restructuring, and augmenting a French treebank: lexicalised parsers or coherent treebanks? [PDF]

open access: yes, 2007
We present the Modified French Treebank (MFT), a completely revamped French Treebank, derived from the Paris 7 Treebank (P7T), which is cleaner, more coherent, has several transformed structures, and introduces new linguistic analyses.
Schluter, Natalie, van Genabith, Josef
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Back-annotation for interactive data path synthesis [PDF]

open access: yes, 1991
In order to take into account physical design effects, a designer needs a feedback mechanism during interactive data path synthesis. In this paper, we propose a hypergraph model and a back-annotation algorithm which provide a feedback mechanism for back ...
Chaiyakul, Viraphol   +2 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy