Results 151 to 160 of about 563,469 (347)
Sex-biased mouse liver lincRNAs: validation and impact of mouse knockout models that perturb hepatic growth signaling [PDF]
, 2016 Sexual dimorphism has a broad impact on human health and disease, including autoimmune diseases, cardiovascular diseases, and liver diseases, specifically hepatocellular carcinoma.
Yilmaz, Feyza
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Treebank-based multilingual unification-grammar development [PDF]
, 2003 Broad-coverage, deep unification grammar development is time-consuming and costly. This problem can be exacerbated in multilingual grammar development scenarios.
Cahill, Aoife +6 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Structural and Functional Annotation of Uncharacterized Protein NCGM946K2_146 of Mycobacterium tuberculosis: An In-Silico Approach [PDF]
, 2020 Abu Saim Mohammad Saikat
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Treebank-based acquisition of a Chinese lexical-functional grammar [PDF]
, 2004 Scaling wide-coverage, constraint-based grammars such as Lexical-Functional Grammars (LFG) (Kaplan and Bresnan, 1982; Bresnan, 2001) or Head-Driven Phrase Structure Grammars (HPSG) (Pollard and Sag, 1994) from fragments to naturally occurring ...
Bodomo, Adams +7 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Communications BiologyProtein functional annotation is crucial in biology, but many protein-coding genes remain uncharacterized, especially in non-model organisms. FANTASIA (Functional ANnoTAtion based on embedding space SImilArity) integrates protein language models for ...
Gemma I. Martínez-Redondo +8 more
doaj +1 more source
Treebank-based acquisition of LFG resources for Chinese [PDF]
, 2007 This paper presents a method to automatically acquire wide-coverage, robust, probabilistic Lexical-Functional Grammar resources for Chinese from the Penn Chinese Treebank (CTB).
Guo, Yuqing +2 more
core