Results 91 to 100 of about 203,888 (281)

Can female urethral calculus present with acute urinary retention?

Formosan Journal of Surgery, 2018
Urethral calculus is a very rare cause obstructive uropathy. Incidence of urethral calculus is extremely rare, less often in females as compared to males. It is usually associated with genitourinary pathology.
M Mahele, M S Faridi, Khumukchum Somarendra Singh, Rajendra Sinam Singh   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Functional Programming and Lambda Calculus [PDF]

, 1990
Contains fulltext : 13246.pdf (Publisher’s version ) (Open Access)
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Linear-algebraic lambda-calculus

, 2005
With a view towards models of quantum computation and/or the interpretation of linear logic, we define a functional language where all functions are linear operators by construction.
Arrighi, Pablo, Dowek, Gilles
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Malliavin calculus and Euclidean quantum mechanics. I. Functional calculus

Journal of Functional Analysis, 1991
The authors state that they give a rigorous version of the functional calculus developed by R. Feynman in relation to his path integral formulation of quantum mechanics, their approach is Euclidean but distinct from the one founded on the Feynman-Kac formula.
Cruzeiro, Ana Bela, Zambrini, Jean-Claude   +1 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Fractional-power approach for solving complete elliptic abstract differential equations with variable-operator coefficients

Electronic Journal of Differential Equations, 2012
This work is devoted to the study of a complete abstract second-order differential equation of elliptic type with variable operators as coefficients.
Fatiha Boutaous, Rabah Labbas, Boubaker-Khaled Sadallah   +2 more
doaj  

Diffeomorphism Invariant Minimization of Functionals with Nonuniform Coercivity

Mathematics
We consider the minimization of a functional of the calculus of variations, under assumptions that are diffeomorphism invariant. In particular, a nonuniform coercivity condition needs to be considered.
Marco Degiovanni, Marco Marzocchi
doaj   +1 more source