Results 121 to 130 of about 278,377 (300)

Mediodorsal thalamic nucleus mediates resistance to ethanol through Cav3.1 T-type Ca2+ regulation of neural activity

eLife
Thalamocortical activity is known to orchestrate sensory gating and consciousness switching. The precise thalamic regions involved, or the firing patterns related to the unconsciousness, remain unclear.
Charles-francois V Latchoumane, Joon-Hyuk Lee, Seong-Wook Kim, Jinhyun Kim, Hee-Sup Shin   +4 more
doaj   +1 more source

The contribution of functional cognition screening during acute illness hospitalization of older adults in predicting participation in daily life after discharge. [PDF]

BMC Geriatr, 2022
Arieli M, Agmon M, Gil E, Kizony R.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Cognition-Oriented Treatments for Older Adults: a Systematic Overview of Systematic Reviews

, 2020
Cognition-oriented treatments – commonly categorized as cognitive training, cognitive rehabilitation and cognitive stimulation – are promising approaches for the prevention of cognitive and functional decline in older adults.
A Lampit (13489747), H Hallock (14653811), HM Gavelin (14653808), J Sabatés (14653814), A Bahar-Fuchs (13673119)   +4 more
core   +1 more source

Cognition, social cognition, and Self-assessment in schizophrenia: prediction of different elements of everyday functional outcomes

, 2019
A growing body of research has shown that two domains of cognition, neurocognition and social cognition, predict different domains of real-world outcomes in people with schizophrenia. Social cognition has been shown to predict social outcomes but not non-
Harvey, Philip D, Silberstein, Juliet
core   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Antipsychotics and cognitive function [PDF]

Psychogeriatrics, 2011
Masako, Azumi, Satoshi, Ishizuka, Masahiko, Fujii, Hidetada, Sasaki   +3 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The relationship between motor function, cognition, independence and quality of life in myelomeningocele patients

Arquivos de Neuro-Psiquiatria
Motor function, cognition, functional independence and quality of life have been described in myelomeningocele patients, but no study has investigated their relationships.
Carolina Lundberg Luz, Maria Clara Drummond Soares de Moura, Karine Kyomi Becker, Rosani Aparecida Antunes Teixeira, Mariana Callil Voos, Renata Hydee Hasue   +5 more
doaj   +1 more source