Results 101 to 110 of about 278,377 (300)

Active and Passive Offline Breaks Differentially Impact the Consolidation of Procedural Motor Memories in Children and Adults

open access: yesBrain and Behavior
Introduction Short post‐learning breaks, lasting from 5 to 30 min, transiently enhance procedural motor memory performance in adults. However, the impact of activity type (active vs.
D. Voisin, P. Peigneux, C. Urbain
doaj   +1 more source

Toward a Selectionist Future in Comparative Cognition

open access: yes
We highlight the persistent problem of using hypothetical constructs as explanations of behavior. We discuss the abandonment of parsimony and the tautologies inherent to explanatory constructs in recent and ongoing topics in the field.
Stahlman, W. David, Leising, Kenneth J.
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Post-Learning Offline Pauses Support Consolidation Beyond the Mind-Wandering State

open access: yesClocks & Sleep
Brief post-learning wakeful resting periods and local sleep mechanisms have been proposed to support offline memory consolidation processes. Mind-wandering (MW), thought to reflect the occurrence or need for local sleep, has been linked to momentary ...
José Costa Dias, Philippe Peigneux
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Visual cognition during real social interaction

open access: yes, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Skarratt, PA, Kuhn, G, Cole, GG
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Impact of CPAP Therapy on Cognition and Fatigue in Patients with Moderate to Severe Sleep Apnea: A Longitudinal Observational Study

open access: yesClocks & Sleep
Continued solicitation of cognitive resources eventually leads to cognitive fatigue (CF), i.e., a decrease in cognitive efficiency that develops during sustained cognitive demands in conditions of constrained processing time, independently of sleepiness.
Oumaïma Benkirane   +2 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Introducing Alternative-Based Thresholding for Defining Functional Regions of Interest in fMRI

open access: yesFrontiers in Neuroscience, 2017
In fMRI research, one often aims to examine activation in specific functional regions of interest (fROIs). Current statistical methods tend to localize fROIs inconsistently, focusing on avoiding detection of false activation.
Jasper Degryse   +5 more
doaj   +1 more source

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