Results 91 to 100 of about 716,371 (239)

Mediating Cognitive Transformation with VR 3D Sketching during Conceptual Architectural Design Process [PDF]

, 2011
Communications for information synchronization during the conceptual design phase require designers to employ more intuitive digital design tools. This paper presents findings of a feasibility study for using VR 3D sketching interface in order to replace
B. Abdullah, Muhamad Taufik, B. Hj Jaafar, Mohd Saleh, Ibrahim, Rahinah, Pour Rahimian, Farzad, Wirza Binti O. K. Rahmat, Rahmita   +4 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Motor learning- and consolidation-related resting state fast and slow brain dynamics across wake and sleep

Scientific Reports
Motor skills dynamically evolve during practice and after training. Using magnetoencephalography, we investigated the neural dynamics underpinning motor learning and its consolidation in relation to sleep during resting-state periods after the end of ...
Liliia Roshchupkina, Vincent Wens, Nicolas Coquelet, Charline Urbain, Xavier de Tiege, Philippe Peigneux   +5 more
doaj   +1 more source

Functional topography of the human entorhinal cortex

eLife, 2015
Despite extensive research on the role of the rodent medial and lateral entorhinal cortex (MEC/LEC) in spatial navigation, memory and related disease, their human homologues remain elusive.
Tobias Navarro Schröder, Koen V Haak, Nestor I Zaragoza Jimenez, Christian F Beckmann, Christian F Doeller   +4 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Contemplating Mindfulness at Work: An Integrative Review [PDF]

, 2015
Mindfulness research activity is surging within organizational science. Emerging evidence across multiple fields suggests that mindfulness is fundamentally connected to many aspects of workplace functioning, but this knowledge base has not been ...
Baer, Ruth A., Bono, Joyce E., Brewer, Judson A., Brown, Kirk W., Duffy, Michelle K., Glomb, Theresa M., Good, Darren J., Lazar, Sara W., Lyddy, Christopher   +8 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Active and Passive Offline Breaks Differentially Impact the Consolidation of Procedural Motor Memories in Children and Adults

Brain and Behavior
Introduction Short post‐learning breaks, lasting from 5 to 30 min, transiently enhance procedural motor memory performance in adults. However, the impact of activity type (active vs.
D. Voisin, P. Peigneux, C. Urbain
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The characteristics of cognitive neuroscience tests in a schizophrenia cognition clinical trial: Psychometric properties and correlations with standard measures. [PDF]

, 2020
In comparison to batteries of standard neuropsychological tests, cognitive neuroscience tests may offer a more specific assessment of discrete neurobiological processes that may be aberrant in schizophrenia.
Ball, M Patricia, Barch, Deanna M, Buchanan, Robert W, Chun, Charlotte A, Csernansky, John G, Goff, Donald C, Gold, James M, Green, Michael F, Jarskog, L Fredrik, Javitt, Daniel C, Keefe, Richard SE, Kern, Robert S, Kimhy, David, Kraus, Michael S, Lieberman, Jeffrey A, Marder, Stephen R, McEvoy, Joseph P, McMahon, Robert P, Mesholam-Gately, Raquelle I, Robinson, James, Seidman, Larry J, Walker, Trina M   +21 more
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