Results 21 to 30 of about 63,859 (253)

Functional Constipation in Children

, 2016
Childhood constipation is a common pediatric healthcare problem. The diagnosis is based on history and physical examination, in accordance with the pediatric diagnostic Rome III criteria. Additional investigations are only indicated if the diagnosis is not clear or in order to rule out an underlying organic disease.
Koppen, Ilan J. N., Benninga, Marc A.
openaire   +2 more sources

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Obesity and functional constipation in children

, 2018
Background Functional constipation is a common pediatric problem in both developed and developing countries.  In the past two decades, the prevalence of obesity has increased worldwide.
Tiangsa Sembiring, Supriatmo Supriatmo, Ade Rachmat Yudiyanto, Natasha Yuwanita, Atan Baas Sinuhaji   +4 more
core   +2 more sources

Butyric acid in functional constipation

Gastroenterology Review, 2013
Butyric acid, a short-chain fatty acid, is a major energy source for colonocytes. It occurs in small quantities in some foods, and in the human body, it is produced in the large intestine by intestinalkacteria. This production can be reduced in some cases, for which butyric acid supplementation may be useful.
Pituch, Aleksandra, Walkowiak, Jarosław, Banaszkiewicz, Aleksandra   +2 more
openaire   +2 more sources

The role of rectal hyposensitivity in the development of functional hindgut disorders: clinical significance and pathophysiology [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorBackground Rectal hyposensitivity (RH) is associated with functional hindgut ...
Burgell, Rebecca Elizabeth
core  

Where Do We Go Wrong in the Pharmacologic Treatment of Functional Constipation in Children? [PDF]

Objective: Constipation is often inadequately treated in childhood, which can lead to psychological problems. This study aimed to evaluate the adequacy of prescribed drugs, dosing, usage, and responses to these drugs in children with functional ...
Kaya, Neslihan Gurcan, Hakan Öztürk, Neslihan Gürcan Kaya, ÖZTÜRK, HAKAN   +3 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Functional Constipation and Fecal Incontinence

, 2020
Constipation and fecal incontinence represent common problems in children. Beyond the neonatal period, only a minority of children have an organic cause for their constipation, and the etiology remains not well understood.
Mana H. Vriesman, Marc A. Benninga, Benninga, Marc A., Vriesman, Mana H.   +3 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source