Results 31 to 40 of about 65,633 (254)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Comparison of Magnesium Values in Functional Constipation and Control Patients

Ahi Evran Medical Journal
Purpose: The objective of this study was to compare serum magnesium levels in patients with functional constipation against a control group. Materials and Methods: This retrospective study included patients diagnosed with functional constipation who ...
Arzu Gülseren, Emine Uçar
doaj   +1 more source

Butyric acid in functional constipation

Gastroenterology Review, 2013
Butyric acid, a short-chain fatty acid, is a major energy source for colonocytes. It occurs in small quantities in some foods, and in the human body, it is produced in the large intestine by intestinalkacteria. This production can be reduced in some cases, for which butyric acid supplementation may be useful.
Aleksandra Pituch-Zdanowska, Walkowiak, J., Aleksandra Marta Banaszkiewicz   +2 more
openaire   +2 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Gut Microbiota and Functional Constipation: Recent Advances in Pathogenesis and Nutritional Interventions [PDF]

Shipin Kexue
With the acceleration of population aging, the problem of functional constipation has become increasingly prominent, significantly affecting the quality of life of the elderly.
DUAN Hao, LIU Gaigai, LU Jiamin, LI Yang, CHANG Xinyue, YANG Tianyu, BAO Shuyuan, SONG Wei, YAN Wenjie
doaj   +1 more source

Faktor dominan kejadian konstipasi fungsional pada remaja di Jakarta

Jurnal Gizi Klinik Indonesia, 2020
Dominant factors of functional constipation among adolescent in Jakarta Background: The impact of functional constipation, including the quality of life decreases, increase the additional health costs that must be incurred, and reduce productivity ...
Felicia Thea, Trini Sudiarti, Kusharisupeni Djokosujono   +2 more
doaj   +1 more source

Managing functional constipation in children [PDF]

Paediatrics & Child Health, 2011
Constipation is a common childhood problem, with both somatic and psychological effects. The etiology of paediatric constipation is likely multifactorial, and seldom due to organic pathology. Children benefit from prompt and thorough management of this disorder.
openaire   +2 more sources

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Somatic Comorbidity in Chronic Constipation: More Data from the GECCO Study

Gastroenterology Research and Practice, 2016
Background. Comorbidity in chronic constipation has rarely been investigated, despite the fact that constipation can occur as one symptom in a number of neurological, systemic, and other nonintestinal and intestinal disorders. Methods.
Paul Enck, Johannes Leinert, Menno Smid, Thorsten Köhler, Juliane Schwille-Kiuntke   +4 more
doaj   +1 more source

Parkinson Disease Subtype Stability and Eventual Convergence

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok, Christina N. Lessov‐Schlaggar, Abdulmunaim M. Eid, Erin R. Foster, Baijayanta Maiti, Hailee Domash, Helen Hwang, Richard J. Perrin, Paul T. Kotzbauer, Joel S. Perlmutter, Meghan C. Campbell   +10 more
wiley   +1 more source