Results 41 to 50 of about 61,716 (253)

COMMUNITY DEVELOPMENT INFLUENCE ON PUBLIC'S KNOWLEDGE IN MANDANGIN ISLAND ABOUT ACUTE DIARRHEA AND FUNCTIONAL CONSTIPATION IN CHILDREN

Journal of Community Medicine and Public Health Research, 2022
In children, acute diarrhea and functional constipation (FC) are still more prevalent in Indonesia, especially in isolated islands, and need comprehensive management.
Reza Gunadi Ranuh, Steven Christian Susianto, Alpha Fardah Athiyyah, Andy Darma, Dwiyanti Puspitasari, Khadijah Rizky Sumitro, Ni Nyoman Metriani Nesa, Muhammad Faizi, Subijanto Marto Sudarmo   +8 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Functional constipation at a young age. Place of macrogol 4000 (Forlax) in the treatment

Gastroenterologìa, 2019
Background. Considering the wide prevalence of functional constipation (FC) at a young age, we set ourselves the task of comparing the effectiveness of osmotic laxative macrogol 4000 (Forlax) in the treatment of FC in adolescents and young adults in the ...
A.E. Dorofeiev, M.M. Rudenko, Yu.V. Zhyhal   +2 more
doaj   +1 more source

Regional and seasonal variations in functional abdominal pain and functional constipation prevalence among Saudi children

SAGE Open Medicine, 2023
Objectives: This study aimed to evaluate functional abdominal pain disorders and functional constipation prevalence in the central region of Saudi Arabia, and compare it to that of the western region.
Ammar Khayat, Sarah Salem Aldharman, Njoud Naif Alharbi, Abdulaziz Saad Alayyaf, Jannat Abdullah abdulmuttalib, Elaf Rudda Altalhi   +5 more
doaj   +1 more source

Acupuncture for the treatment of functional constipation

Journal of Traditional Chinese Medicine, 2016
To assess the effectiveness of acupuncture for the treatment of functional constipation (FC).The literature was searched for randomized controlled trials (RCTs) comparing acupuncture with medical treatment; no medical treatment, placebo acupuncture, and sham acupuncture in patients with FC were searched. Data were extracted by two independent reviewers
Tao, Bai, Chao, Song, Cuihong, Zheng, Guangying, Huang   +3 more
openaire   +2 more sources

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

The effect of mother’s and infant nutrition on functional constipation in children between 1-4 months

Trends in Pediatrics
Objective: Constipation is the infrequent and painful passage of hardened stools, occurring less than three times a week, often accompanied by excessive straining and discomfort.
Gülberat Totur, Maşallah Baran
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source