Results 61 to 70 of about 57,558 (262)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Multivariate information theory uncovers synergistic subsystems of the human cerebral cortex
One of the most well-established tools for modeling the brain is the functional connectivity network, which is constructed from pairs of interacting brain regions.
Thomas F. Varley +3 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Defines the basic structural-elements of functioning of a system of information telemetry ensuring starts rockets of space appointment. The contents of information processes in the system of information telemetry ensuring starts rockets of space ...
A.V. Kuimov, A.V. Kononenko
doaj
A malware detection method with function parameters encoding and function dependency modeling [PDF]
As computers are widely used in people’s work and daily lives, malware has become an increasing threat to network security. Although researchers have introduced traditional machine learning and deep learning methods to conduct extensive research on ...
Ronghao Hou +4 more
doaj +2 more sources
Background From a theoretical ecology point of view, microbiomes are far more complex than expected. Besides competition and competitive exclusion, cooperative microbe-microbe interactions have to be carefully considered.
Alice Mataigne +3 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
On the Family of Conditional Embedded Implicational Dependencies [PDF]
Certain second-order sentences, called conditional embedded implicational dependencies, about relations in a relational database, are defined and studied. This class of dependencies includes some of previously defined dependencies as special cases. Thus,
Victor Felea
doaj

