Results 61 to 70 of about 3,269,321 (296)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Spatiotemporal adaptive attention graph convolution network for city-level air quality prediction

Scientific Reports, 2023
Air pollution is a leading cause of human diseases. Accurate air quality predictions are critical to human health. However, it is difficult to extract spatiotemporal features among complex spatiotemporal dependencies effectively.
Hexiang Liu, Qilong Han, Hui Sun, Jingyu Sheng, Ziyu Yang   +4 more
doaj   +1 more source

Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling.

PLoS Computational Biology, 2022
The development of cancer therapies may be improved by the discovery of tumor-specific molecular dependencies. The requisite tools include genetic and chemical perturbations, each with its strengths and limitations.
Alina Batzilla, Junyan Lu, Jarno Kivioja, Kerstin Putzker, Joe Lewis, Thorsten Zenz, Wolfgang Huber   +6 more
doaj   +1 more source

Monoidal functional dependencies

Journal of Computer and System Sciences, 2015
We present a complete logic for reasoning with functional dependencies (FDs) with semantics defined over classes of commutative integral partially ordered monoids and complete residuated lattices. The dependencies allow us to express stronger relationships between attribute values than the ordinary FDs. In our setting, the dependencies not only express
openaire   +4 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

sbmlteam/libSBML-dependencies: Release 1.0.1

, 2022
Release of all dependencies needed for all potential build options for libSBML. This version includes current versions for expat, libxml and xerces-c.Set of dependencies for compiling ...
Michael Hucka
core   +1 more source

Methodical bases of functioning of the system model information and telemetric ensuring starts of rockets of space appointment

Физика волновых процессов и радиотехнические системы, 2018
Defines the basic structural-elements of functioning of a system of information telemetry ensuring starts rockets of space appointment. The contents of information processes in the system of information telemetry ensuring starts rockets of space ...
A.V. Kuimov, A.V. Kononenko
doaj  

Multi-genome metabolic modeling predicts functional inter-dependencies in the Arabidopsis root microbiome

Microbiome, 2022
Background From a theoretical ecology point of view, microbiomes are far more complex than expected. Besides competition and competitive exclusion, cooperative microbe-microbe interactions have to be carefully considered.
Alice Mataigne, Nathan Vannier, Philippe Vandenkoornhuyse, Stéphane Hacquard   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source