Results 91 to 100 of about 1,214,259 (255)

Mangrove microniches determine the structural and functional diversity of enriched petroleum hydrocarbon-degrading consortia [PDF]

, 2010
In this study, the combination of culture enrichments and molecular tools was used to identify bacterial guilds, plasmids and functional genes potentially important in the process of petroleum hydrocarbon (PH) decontamination in mangrove microniches ...
Baek, Bale, Barac, Bartilson, Beeson, Benson, Bosch, Brito, Cecilia G. Flocco, Chou, Clarke, Costa, Das, Dennis, Dietmar H. Pieper, Dionisi, Ellen Krögerrecklenfort, Eltis, Entcheva, Eulberg, Fox, Fulthorpe, Germaine, Gomes, Gomes, Gomes, Gomes, Grayston, Götz, Harris, Head, Hedge, Heuer, Heuer, Hoff, Howard Junca, Izmalkova, Jaeger, Jeon, Junca, Koren, Kornelia Smalla, Krasowiak, Kuiper, Kummerová, Laurie, Leda C.S. Mendonça-Hagler, Lloyd-Jones, MacCormack, Margesin, Milling, Moser, Nakai, Nam, Neumann, Newton C.M. Gomes, Palleroni, Pleshakova, Proffitt, Pukall, Pérez-Pantoja, Ramette, Ramiro Vilchez, Rasmussen, Rodolfo Paranhos, Rodrigo Costa, Sambrook, Sar, Schlüter, Seo, Smalla, Smalla, Smits, Sobecky, Sota, Van Hamme, Venosa, Wang, Widada, Wilson, Wongsa, Yakimov   +81 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Complex dynamics in coevolution models with ratio-dependent functional response

, 2009
We explore the complex dynamical behavior of two simple predator-prey models of biological coevolution that on the ecological level account for interspecific and intraspecific competition, as well as adaptive foraging behavior.
Bascompte, Caldarelli, Chowdhury, Chowdhury, Christensen, Crosby, di Collobiano, Drossel, Drossel, Eigen, Eigen, Filotas, Gavrilets, Gavrilets, Gavrilets, Getz, Hall, Kauffman, Kauffman, Krebs, Krebs, Kuang, Martinez, Murray, Namba, Newman, Newman, Nunes Amaral, Per Arne Rikvold, Procaccia, Qin, Quince, Quince, Resit, Rikvold, Rikvold, Rikvold, Rikvold, Rossberg, Rossberg, Sevim, Skalski, Solé, Thompson, Thompson, Verhulst, Yoshida, Yoshida, Zia   +48 more
core   +1 more source

Coherent regimes of globally coupled dynamical systems [PDF]

, 2003
The paper presents a method by which the mean field dynamics of a population of dynamical systems with parameter diversity and global coupling can be described in terms of a few macroscopic degrees of freedom.
d'Ovidio, Francesco, De Monte, Silvia, Mosekilde, Erik   +2 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationships between functional alpha and beta diversities of flea parasites and their small mammalian hosts

Parasitology
We studied the relationships between functional alpha and beta diversities of fleas and their small mammalian hosts in 4 biogeographic realms (the Afrotropics, the Nearctic, the Neotropics and the Palearctic), considering 3 components of alpha diversity (
Boris R. Krasnov, Irina S. Khokhlova, M. Fernanda López Berrizbeitia, Sonja Matthee, Juliana P. Sanchez, Georgy I. Shenbrot, Luther van der Mescht   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Parsimonious Labeling [PDF]

, 2015
We propose a new family of discrete energy minimization problems, which we call parsimonious labeling. Specifically, our energy functional consists of unary potentials and high-order clique potentials. While the unary potentials are arbitrary, the clique
Dokania, Puneet K., Kumar, M. Pawan
core   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source