Results 71 to 80 of about 1,772,774 (288)

Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]

open access: yes, 2020
With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria   +3 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Pattern of functional diversity along the elevation gradient in the dry evergreen Afromontane forest of Hararghe Highland, Southeast Ethiopia

open access: yesBiosystems Diversity, 2020
Understanding plant species distribution patterns along environmental gradients is fundamental to managing ecosystems, particularly when habitats are fragmented due to intensive human land use pressure.
M. Teshome, Z. Asfaw, M. Mohammed
doaj   +1 more source

Above and belowground community strategies respond to different global change drivers [PDF]

open access: yes, 2019
Environmental changes alter the diversity and structure of communities. By shifting the range of species traits that will be successful under new conditions, environmental drivers can also dramatically impact ecosystem functioning and resilience.
Adair, Karen L.   +6 more
core   +1 more source

Functional diversity of natural IgM [PDF]

open access: yesInternational Immunology, 1999
This paper proposes a method for the quantitative characterization of repertoire diversity of an unknown mixture of antibodies on the basis of its reactivity profile in the quantitative immunoblot (QIB). The QIB is calibrated by measuring the reactivity profiles of supernatants of known 'diversity' (i.e. known numbers of B cell clones).
C, Brissac   +3 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Atlantic Dung Beetle Traits: A comprehensive dataset of functional traits for dung beetles (Coleoptera, Scarabeidae, Scarabaeinae) in the Atlantic Forest [PDF]

open access: yesBiodiversity Data Journal
Functional traits offer critical insights into species performance, survival strategies and ecological interactions. However, the availability of comprehensive trait datasets remains limited, primarily due to the substantial effort required for field ...
Paula Ribeiro Anunciação   +5 more
doaj   +3 more sources

The role of climate and plant functional trade-offs in shaping global biome and biodiversity patterns

open access: yes, 2011
Aim: Two of the oldest observations in plant geography are the increase in plant diversity from the poles towards the tropics and the global geographic distribution of vegetation physiognomy (biomes). The objective of this paper is to use a process-based
Ackerly   +47 more
core   +1 more source

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