Results 91 to 100 of about 9,135 (286)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Indistinguishability Obfuscation from Functional Encryption [PDF]

, 2018
© 2018 Association for Computing Machinery. Indistinguishability obfuscation (IO) is a tremendous notion, powerful enough to give rise to almost any known cryptographic object.
Bitansky, Nir, Vaikuntanathan, Vinod, Nir Bitansky, Vinod Vaikuntanathan   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Impossibility Results for Lattice-Based Functional Encryption Schemes [PDF]

, 2023
Functional Encryption denotes a form of encryption where a master secret key-holder can control which functions a user can evaluate on encrypted data.
Akin Ünal
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The DaTa Encryption Based on Discrete Chaotic SYSTEMS AND MAPS

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The encryption algorithm based on scheme of block symmetric encryption algorithm and used the discrete chaotic systems and maps is presented. Comparative analysis of encryption sets by delayed coordinate method and construction of phase diagrams with ...
A. V. Sidorenko, K. S. Mulyarchik
doaj  

Implementation of Ring Learning-with-Errors Encryption and Brakerski–Fan–Vercauteren Fully Homomorphic Encryption Using ChatGPT

Computers
This paper investigates whether ChatGPT, a large language model, can assist in the implementation of lattice-based cryptography and fully homomorphic encryption algorithms, specifically the Ring Learning-with-Errors encryption scheme and the Brakerski ...
Zhigang Chen, Xinxia Song, Liqun Chen, Hai Liu   +3 more
doaj   +1 more source

Security of Functionally Obfuscated DSP Core Against Removal Attack Using SHA-512 Based Key Encryption Hardware

IEEE Access, 2019
Digital signal processing (DSP) kernel-based intellectual property (IP) core forms an integral ingredient of consumer electronics devices. Thus, protection of these IP cores against reverse engineering attack is crucial.
Anirban Sengupta, Mahendra Rathor
doaj   +1 more source

Flexible multi-client functional encryption for set intersection. [PDF]

J Supercomput, 2023
Rafiee M.
europepmc   +1 more source