Results 71 to 80 of about 9,135 (286)
Functional encryption for cascade automata
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Dan Brownstein, Shlomi Dolev, Niv Gilboa
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Multi-input Functional Encryption [PDF]
We introduce the problem of Multi-Input Functional Encryption, where a secret key sk f can correspond to an n-ary function f that takes multiple ciphertexts as input. We formulate both indistinguishability-based and simulation-based definitions of security for this notion, and show close connections with indistinguishability and virtual black-box ...
Shafi Goldwasser +8 more
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Advances in Functional Encryption [PDF]
Functional encryption is a novel paradigm for public-key encryption that enables both fine-grained access control and selective computation on encrypted data, as is necessary to protect big, complex data in the cloud.
Wee, Hoeteck
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
AbstractFunctional encryption gives users fine-grained access to the encrypted data and permits the computation of specific functions on the protected plaintexts. Namely, data is encrypted using a public key, while restricted keys that correspond to particular functions are generated.
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The advent of the digital era and computer-based remote communications has significantly enhanced the applicability of various sciences over the past two decades, notably data science (DS) and cryptography (CG).
Banaeian Far Saeed, Imani Rad Azadeh
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

