Results 91 to 100 of about 191,132 (268)

Euler's Beta function diagonalized and a related functional equation [PDF]

open access: yesOpuscula Mathematica, 2004
Euler's Gamma function is the unique logarithmically convex solution of the functional equation \[\varphi(x+1)=x\varphi(x),\quad x\in\mathbb{R}_{+};\quad \varphi(1)=1,\] cf. the Proposition. In this paper we deal with the function \(\beta :\mathbb{R}_{+}\
Bodgan Choczewski, Anna Wach-Michalik
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

On the stability of generalized gamma functional equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2000
We obtain the Hyers-Ulam stability and modified Hyers-Ulam stability for the equations of the form g(x+p)=φ(x)g(x) in the following settings: |g(x+p)−φ(x)g(x)|≤δ,   |g(x+p)−φ(x)g(x)|≤ϕ(x),   |(g(x+p)/φ(x)g(x))−1|≤ψ(x).
Gwang Hui Kim
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Reducible functional differential equations

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1985
This is the first part of a survey on analytic solutions of functional differential equations (FDE). Some classes of FDE that can be reduced to ordinary differential equations are considered since they often provide an insight into the structure of ...
S. M. Shah, Joseph Wiener
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

On Hecke’s functional equation [PDF]

open access: yesBulletin of the American Mathematical Society, 1961
Chandrasekharan, K.   +1 more
openaire   +3 more sources

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