Results 61 to 70 of about 178,723 (265)

Orthogonal Stability and Solution of a Three-Variable Functional Equation in Extended Banach Spaces

Mathematics
This manuscript introduces a novel three-variable cubic functional equation and derives its general solution. Employing both the direct and fixed-point methods, we investigate the orthogonal stability of this equation within the frameworks of quasi-β ...
Jagjeet Jakhar, Shalu Sharma, Jyotsana Jakhar, Majeed A. Yousif, Pshtiwan Othman Mohammed, Alina Alb Lupas, Nejmeddine Chorfi   +6 more
doaj   +1 more source

Eigenvalues and Functional Equations [PDF]

Proceedings of the American Mathematical Society, 1957
Abstract : The purpose of this paper was to illustrate how the techniques of the theory of dynamic programming may be used to convert a number of eigenvalue problems, where one is interested only in maximum or minimum values, into problems involving recurrence relations.
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A Noninformative Prior on a Space of Distribution Functions

Entropy, 2017
In a given problem, the Bayesian statistical paradigm requires the specification of a prior distribution that quantifies relevant information about the unknowns of main interest external to the data.
Alexander Terenin, David Draper
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A numerical technique based on Lucas polynomials together with standard and Chebyshev-Lobatto collocation points for solving functional integro-differential equations involving variable delays

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
In this paper, a new numerical matrix-collocation technique is consideredto solve functional integro-differential equations involving variable delaysunder the initial conditions.
Sevin Gümgüm, Nurcan Baykuş Savaşaneril, Ömür Kıvanç Kürkçü, Mehmet Sezer   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Properties of a Composite Material with Mixed Imperfect Contact Conditions

Mathematical Modelling and Analysis, 2016
We present an analytical solution of a mixed boundary value problem for an unbounded 2D doubly periodic domain which is a model of a composite material with mixed imperfect interface conditions.
Luıs Filipe Pinheiro de Castro, Ekaterina Pesetskaya   +1 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Generalization of sum representation functional equations-I

International Journal of Mathematics and Mathematical Sciences, 1979
This paper contains the solution of a functional equation which is a generalization of a functional equation arising in a characterization of directed divergence and inaccuracy.
Pl. Kannappan, V. Sathyabhama
doaj   +1 more source