Results 41 to 50 of about 60,168 (264)

On the period function for a family of complex differential equations

open access: yesJournal of Differential Equations, 2006
Planar differential equations of the form \(\dot{z}=f(z)g(\overline{z})\), where \(f(z)\) and \(g(z)\) holomorphic functions, are considered, and it is proven that if \(g(z)\) is not constant then for any continuum of period orbits, the period function has at most one isolated critical period, which is a minimum.
Garijo, Antonio   +2 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ON THE PROBLEM OF LOGIC-AUTOMATIC FORMULAS PERFORMABILITY

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. In the theory of finite automata, there are a number of ways to define finite automata (finitely automatic functions). There are systems of canonical equations among them, Moore diagrams, information trees, schemes of automatic elements ...
S. S. Marchenkov
doaj   +1 more source

USE OF A NUMERICAL ANALYTICAL MODEL FOR ASSESSING THE FUNCTIONAL EFFECTIVENESS OF AN INFORMATION PROTECTION SYSTEM BY ANALYSING ITS PROBABILISTIC-TEMPORAL CHARACTERISTICS

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2020
. Aim Currently, the implementation of computational experiments to determine the probabilistic-temporal characteristics of protection functions for automated information systems is a complex and costly task. In order to study the dynamics of transitions
V. P. Alferov   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Calculation of the decomposition coefficients for plane contact problem kernel in the orthonormal basis

open access: yesApplied and Computational Mechanics
Analytical solutions of some contact problems are infinite functional series according to the system of basic functions. When constructing such solutions, it becomes necessary to represent the kernels of integral equations describing the process of ...
Kazakov K. E.
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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