Results 51 to 60 of about 63,506 (264)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Multiscale modeling, stochastic and asymptotic approaches for analyzing neural networks based on synaptic dynamics

open access: yesESAIM: Proceedings and Surveys, 2014
How do neurons coordinate in complex networks to achieve higher brain functions? Answering this question has relied on experimental approaches based on functional imaging, electrophysiology and microscopy imaging, but surprisingly ...
Holcman D.
doaj   +1 more source

Discrete Sequential Information Coding: Heteroclinic Cognitive Dynamics

open access: yesFrontiers in Computational Neuroscience, 2018
Discrete sequential information coding is a key mechanism that transforms complex cognitive brain activity into a low-dimensional dynamical process based on the sequential switching among finite numbers of patterns.
Mikhail I. Rabinovich, Pablo Varona
doaj   +1 more source

Response Functions of Spiral Wave Solutions of the Complex GinzburgsLandau Equation [PDF]

open access: yesJournal of Non-linear Mathematical Physics, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Biktasheva, I. V., Biktashev, V. N.
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Variational problem of adaptive optimal control. Theoretical and applied computer analysis

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
The problem of adaptive optimal control of a dynamical system, which belongs to the class of conditional variational problems with moving boundaries, is considered. A variational and computer study of the controlled adaptive motion of a material point is
A. A. Vedyakov   +3 more
doaj   +1 more source

Assessing lateral flows and solute transport during floods in a conduit-flow-dominated karst system using the inverse problem for the advection–diffusion equation [PDF]

open access: yesHydrology and Earth System Sciences, 2017
The aim of this study is to present a framework that provides new ways to characterize the spatio-temporal variability of lateral exchanges for water flow and solute transport in a karst conduit network during flood events, treating both the diffusive ...
C. Cholet   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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