Results 41 to 50 of about 63,391 (265)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ON THE PROBLEM OF LOGIC-AUTOMATIC FORMULAS PERFORMABILITY

Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. In the theory of finite automata, there are a number of ways to define finite automata (finitely automatic functions). There are systems of canonical equations among them, Moore diagrams, information trees, schemes of automatic elements ...
S. S. Marchenkov
doaj   +1 more source

A Novel Approach for Simulation of Automotive Radar Sensors Designed for Systematic Support of Vehicle Development

Sensors, 2023
Despite the progress in driving automation, the market introduction of higher-level automation has not yet been achieved. One of the main reasons for this is the effort in safety validation to prove functional safety to the customer.
Zoltan Ferenc Magosi, Arno Eichberger
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Abundant Non-Traveling Fractal Solutions of Dromion Type for the Extended Hirota–Satsuma–Ito Equation

Fractal and Fractional
This paper aims to explore non-traveling fractal solutions to an extended Hirota–Satsuma–Ito equation (gHSI) that contains several well-known equations arising in fluid dynamics.
Mohammed Alkinidri, Shami A. M. Alsallami   +1 more
doaj   +1 more source

USE OF A NUMERICAL ANALYTICAL MODEL FOR ASSESSING THE FUNCTIONAL EFFECTIVENESS OF AN INFORMATION PROTECTION SYSTEM BY ANALYSING ITS PROBABILISTIC-TEMPORAL CHARACTERISTICS

Вестник Дагестанского государственного технического университета: Технические науки, 2020
. Aim Currently, the implementation of computational experiments to determine the probabilistic-temporal characteristics of protection functions for automated information systems is a complex and costly task. In order to study the dynamics of transitions
V. P. Alferov, A. V. Butskikh, A. V. Krisilov, A. D. Popov, E. A. Rogozin   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Calculation of the decomposition coefficients for plane contact problem kernel in the orthonormal basis

Applied and Computational Mechanics
Analytical solutions of some contact problems are infinite functional series according to the system of basic functions. When constructing such solutions, it becomes necessary to represent the kernels of integral equations describing the process of ...
Kazakov K. E.
doaj   +1 more source