Results 41 to 50 of about 71,517 (254)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Positive Periodic Solutions in Shifts δ± for a Class of Higher-Dimensional Functional Dynamic Equations with Impulses on Time Scales

Abstract and Applied Analysis, 2014
Let T⊂R be a periodic time scale in shifts δ± with period P∈(t0,∞)T and t0∈T is nonnegative and fixed. By using a multiple fixed point theorem in cones, some criteria are established for the existence and multiplicity of positive solutions in shifts δ ...
Meng Hu, Lili Wang, Zhigang Wang
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A finite bidimensional wavelet framework for computer graphics

CLEI Electronic Journal, 2008
A lot of material has been written about wavelet theory. Most of these texts provide an elegant framework from the functional and real analysis point of view.
Francisco José Benavides Murillo, Edgar Benavides Murillo, Francisco J. Torres-Rojas   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Mathematical optimization approach for estimating the quantum yield distribution of a photochromic reaction in a polymer

AIP Advances, 2017
The convolution of a series of events is often observed for a variety of phenomena such as the oscillation of a string. A photochemical reaction of a molecule is characterized by a time constant, but materials in the real world contain several molecules ...
Mirai Tanaka, Takashi Yamashita, Natsuki Sano, Aya Ishigaki, Tomomichi Suzuki   +4 more
doaj   +1 more source

Unconventional analogs of single-parametric method of iterational aggregation

Karpatsʹkì Matematičnì Publìkacìï, 2018
When we solve practical problems that arise, for example, in mathematical economics, in the theory of Markov processes, it is often necessary to use the decomposition of operator equations using methods of iterative aggregation.
I.I. Demkiv, M.I. Kopach, A.F. Obshta, B.A. Shuvar   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source