Results 81 to 90 of about 9,169,303 (329)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Artificial Examples of Empirical Equivalence [PDF]

open access: yes, 2013
In this paper I analyze three artificial examples of empirical equivalence: van Fraassen’s alternative formulations of Newton’s theory, the Poincaré-Reichenbach argument for the conventionality of geometry; and predictively equivalent ‘systems of the ...
Acuña, Pablo
core  

Stimulus Equivalence: A Laboratory Artefact or the Heart of Language? [PDF]

open access: yes
This thesis surveys some of the implications of the presented collection of publications, all of which address the phenomenon of stimulus equivalence.
Dickins, David
core   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Problems in the theoretical foundation of the functional-equivalent approach

open access: yesActa Theologica, 2002
The functional-equivalent approach to Bible translation is based on a specific view of communication, viz. that it is a process which takes place within a closed cultural circle. This view of  communication results in a view of the Bible as a time-bound
G. J. C. Jordaan
doaj   +1 more source

Differentiable Functions Equivalent to Analytic Functions

open access: yesPublications of the Research Institute for Mathematical Sciences, 1973
1. Let jf, g be real-valued functions of class C in R. Functions /, g are called equivalent if there exists a diffeomorphism (of class C°°) r of R such that f°t=g. The main object of this paper is to show under what conditions a function is equivalent to an analytic function (Theorem i). In the case of polynomials, the corresponding result is proved in
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Stable Equivalence over Symmetric Functions [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2005
By using cutting strips and transformations on outside decompositions of a skew diagram, we show that the Giambelli-type matrices for a given skew Schur function are stably equivalent to each other over symmetric functions. As a consequence, the Jacobi-Trudi matrix and the transpose of the dual Jacobi-Trudi matrix are stably equivalent over symmetric ...
William Y. C. Chen, Arthur L. B. Yang
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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