Results 101 to 110 of about 9,169,303 (329)

Implications of epigenetic variability within a cell population for cell type classification

open access: yesFrontiers in Behavioral Neuroscience, 2015
Here we propose a new approach to defining nerve ‘cell types’ in reaction to recent advances in single cell analysis. Among cells previously thought to be equivalent, considerable differences in global gene expression and biased tendencies among ...
Inna eTabansky   +4 more
doaj   +1 more source

A million variables and more: the Fast Greedy Equivalence Search algorithm for learning high-dimensional graphical causal models, with an application to functional magnetic resonance images

open access: yesInternational Journal of Data Science and Analysis, 2016
We describe two modifications that parallelize and reorganize caching in the well-known Greedy Equivalence Search algorithm for discovering directed acyclic graphs on random variables from sample values.
Joseph Ramsey   +3 more
semanticscholar   +1 more source

Polyhedrons and Perceptrons Are Functionally Equivalent

open access: yesCoRR, 2013
Mathematical definitions of polyhedrons and perceptron networks are discussed. The formalization of polyhedrons is done in a rather traditional way. For networks, previously proposed systems are developed. Perceptron networks in disjunctive normal form (DNF) and conjunctive normal forms (CNF) are introduced.
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Functional equivalence and domestication strategies in film translation

open access: yes, 2008
One of the charges made against Nida's theory of dynamic equivalence is that “if we follow his injunction to preserve the genius of the target language, it will mean suppressing the Otherness of the source language” (Fawcett 1997).
I. Parini
core   +1 more source

Carotenoid metabolic profiling and transcriptome‐genome mining reveal functional equivalence among blue‐pigmented copepods and appendicularia

open access: yesMolecular Ecology, 2014
The tropical oligotrophic oceanic areas are characterized by high water transparency and annual solar radiation. Under these conditions, a large number of phylogenetically diverse mesozooplankton species living in the surface waters (neuston) are found ...
Nazia Mojib   +5 more
semanticscholar   +1 more source

Equivalent functions for the Fresnel integral

open access: yesOptics Express, 2005
Fresnel integral is modeled with three equivalent functions. The first function is derived by considering the sum of the first term of the Fresnel integral's asymptotic expansion {F(x)} and an exponential function which approaches to infinity at the zero of the Fresnel function's argument and has the properties of a unit step function.
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

FUNDIO: a lambda-calculus with letrec, case, constructors, and an IO-interface : approaching a theory of unsafePerformIO [PDF]

open access: yes, 2003
This paper proposes a non-standard way to combine lazy functional languages with I/O. In order to demonstrate the usefulness of the approach, a tiny lazy functional core language FUNDIO , which is also a call-by-need lambda calculus, is investigated. The
Schmidt-Schauß, Manfred
core  

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