Results 31 to 40 of about 535,935 (302)

Evolutionary dynamics of tumor progression with random fitness values

, 2010
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations,
Becskei, Beerenwinkel, Beisel, Bodmer, Coldman, Cowperthwaite, Durrett, Durrett, Elowitz, Feinerman, Frank, Franziska Michor, Gillespie, Gillespie, Goldie, Goldie, Haeno, Imhof, Iwasa, Iwasa, Jasmine Foo, John Mayberry, Kaern, Kassen, Kevin Leder, Knudson, Komarova, Maclean, Maley, Maley, Michor, Michor, Michor, Nowak, Nowell, Orr, Rick Durrett, Rokyta, Rozen, Sanjuán, Schweinsberg, Shah, Weissman, Wodarz   +43 more
core   +1 more source

Ground Reaction Forces and Impact Loading Among Runners with Different Acuity of Tibial Stress Injuries: Advanced Waveform Analysis for Running Mechanics

Bioengineering
Conventional ground reaction force (GRF) and load rate (LR) analyses may overlook temporal and waveform characteristics that reflect injury status and acuity.
Ryan M. Nixon, Sharareh Sharififar, Matthew Martenson, Lydia Pezzullo, Kevin R. Vincent, Heather K. Vincent   +5 more
doaj   +1 more source

Accuracy of self-reported foot strike pattern detection among endurance runners

Frontiers in Sports and Active Living
IntroductionFoot strike pattern is often associated with running related injury and the focus of training and rehabilitation for athletes. The ability to modify foot strike pattern depends on awareness of foot strike pattern before being able to attempt ...
Heather K. Vincent, Kyle Coffey, Aiden Villasuso, Kevin R. Vincent, Sharareh Sharififar, Lydia Pezzullo, Ryan M. Nixon   +6 more
doaj   +1 more source

Analysis of the adaptive effect in female athletes at the pre-competition stage of the annual educational and training macrocycle

Спортивная медицина: наука и практика, 2020
Aim: assessment of the functional state of female students of the sports department of the university involved in track and field athletics at the pre-competition stage of the annual training cycle. Materials and methods.
S. V. Gudimov, A. N. Shkrebko, I. A. Osetrov, V. M. Shaimardanov   +3 more
doaj   +1 more source

The psychometric function: I. Fitting, sampling, and goodness of fit [PDF]

Perception & Psychophysics, 2001
The psychometric function relates an observer's performance to an independent variable, usually some physical quantity of a stimulus in a psychophysical task. This paper, together with its companion paper (Wichmann & Hill, 2001), describes an integrated approach to (1) fitting psychometric functions, (2) assessing the goodness of fit, and (3) providing
Wichmann, F., Hill, N.
openaire   +3 more sources

Impact of the level of physical activities on emotional exhaustion, depersonalization, lack of personal accomplishment and burnout among students in the city province of Kinshasa

Turkish Journal of Kinesiology
The impact of the practice of physical activities on burnout and its dimensions remains very little documented among students living in subaerial African countries.
Liny Enyuka Kila, Constant Nkıama, Dalmond Kambale Mutsopi, Siloé Ntumba Tshiyamba, Carel Busano Nduakulu, Godefroid Kusuayi Mabele   +5 more
doaj   +1 more source

Adapted physical activity: Benefit on oxidative, functional capacity and exercise tolerance of elderly people in Kinshasa

Turkish Journal of Kinesiology
In basketball, shooting stands out as a vital technique directly affecting the game results. Identifying shooting mechanics early in a basketball player's career can significantly develop shooting performance in subsequent years.
Constant Nkıama, Samuel Biduaya Bamu, Carel Busano Nduakulu, Siloé Ntumba Tshiyamba, Godefroid Kusuayi   +4 more
doaj   +1 more source

Exaptation and emergence as mechanisms to cross fitness valleys during evolution: an example using simulated homing behaviour [PDF]

, 2008
Evolution is often considered a gradual hill climbing process, slowly increasing the fitness of organisms. I investigate the evolution of homing behaviour in simulated intertidal limpets.
Richard Stafford
core   +1 more source

Transgressivity in Key Functional Traits Rather Than Phenotypic Plasticity Promotes Stress Tolerance in A Hybrid Cordgrass [PDF]

, 2019
Hybridization might promote offspring fitness via a greater tolerance to environmental stressors due to heterosis and higher levels of phenotypic plasticity.
Castillo Segura, Jesús Manuel, Drenovsky, Rebecca E., Gallego Tévar, Blanca, Grewell, Brenda J.   +3 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source