Results 71 to 80 of about 188,059 (261)

Corrigendum: Effects of Whole Body Electrostimulation Associated With Body Weight Training on Functional Capacity and Body Composition in Inactive Older People

Frontiers in Physiology, 2021
Alexandre Lopes Evangelista, Angelica Castilho Alonso, Raphael M. Ritti-Dias, Bruna Massaroto Barros, Cleison Rodrigues de Souza, Tiago Volpi Braz, Danilo Sales Bocalini, Julia Maria D'andréa Greve   +7 more
doaj   +3 more sources

Le processus incapacitant au cours du vieillissement : rôle de l’exercice/activité physique

Bulletins et Mémoires de la Société d’Anthropologie de Paris, 2007
Aging is a phenomenon of increased importance in contemporaneous societies. Although it is well established that physical exercise/activity contributes to maintain functional fitness at optimal levels, physical inactivity is a largely prevalent behaviour
Philipe de Souto Barreto, Anne-Marie Ferrandez   +1 more
doaj   +1 more source

Assessment of the efficiency of cognitive function of people over 65

Journal of Education, Health and Sport, 2018
Demographic estimates for Poland indicate that the average life expectancy of the population will increase further over the next decades. Weakness of memory is a physiological phenomenon affecting about 60% of people over 65, whereas the prevalence of ...
Katarzyna Tomaszewska, Bożena Majchrowicz, Alicja Kłos   +2 more
doaj   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Aptidão funcional de idosos residentes em uma instituição de longa permanência

Revista Brasileira de Geriatria e Gerontologia
OBJETIVO: Avaliar a aptidão funcional e as variáveis antropométricas de idosos independentes e semidependentes residentes em uma Instituição de Longa Permanência para Idosos (ILPI) de Florianópolis/SC.
Patrícia Daura de Souza, Tânia R. Bertoldo Benedetti, Lucélia Justino Borges, Giovana Zaperllon Mazo, Lúcia H. Takase Gonçalves   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Evolutionary Art with an EEG Fitness Function [PDF]

, 2019
This project involved the use of an interactive Genetic Al-gorithm (iGA) with an electroencephalogram (EEG)-based fitness function to create paintings in the style of Piet Mondrian, a Dutch painter who used geometric elements in his later paintings. Primary data for the prototype was gathered by analysis of twenty-seven existing Mondrian paintings.
Ingrid Nemecková, Carl James-Reynolds, Edward Currie   +2 more
openaire   +1 more source

Functional and motor fitness of 7-8 form pupils as factor of health improvement

Journal of Education, Health and Sport, 2017
Ivashchenko Olga, Kuznetsova Olena, Zukow Walery. Functional and motor fitness of 7-8 form pupils as factor of health improvement. Journal of Education, Health and Sport. 2016;6(11):325-328. eISSN 2391-8306.
Olga Ivashchenko, Olena Kuznetsova, Walery Zukow   +2 more
doaj