Results 221 to 230 of about 2,588,001 (311)

Screening of functional genes affecting the quality of translucent eggshell membranes based on RNA-seq analysis and DIA proteomics. [PDF]

Front Vet Sci
Han CH, Zhao XY, Wang CW, Xu LJ, Liu HG, Chen H, Zhou RY, Wang DH.   +7 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (<i>Nelumbo</i>). [PDF]

Front Plant Sci
He J, Ma Y, Liu Q, Zhang R, Huang G, Zhang D, Liu F, Yang C.   +7 more
europepmc   +1 more source

Gene associations — SNPs and function

Journal of Neuroimmunology, 2011
openaire   +3 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Impact of Biochar on Nitrogen-Cycling Functional Genes: A Comparative Study in Mollisol and Alkaline Soils. [PDF]

Life (Basel)
Ding J, Yu S.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Correction: Metagenomic analysis reveals rumen microbiome enrichment and functional genes adjustment in carbohydrate metabolism induced by different sorting behavior in mid-lactation dairy cows. [PDF]

Anim Microbiome
Mousa AA, Zhang H, Duan H, Zhang J, Mao S.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Metagenomic analysis reveals rumen microbiome enrichment and functional genes adjustment in carbohydrate metabolism induced by different sorting behavior in mid-lactation dairy cows. [PDF]

Anim Microbiome
Mousa AA, Zhang H, Duan H, Zhang J, Mao S.   +4 more
europepmc   +1 more source