Results 231 to 240 of about 2,594,564 (358)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Effects of fire intensity on soil microbial diversity and nitrogen cycling functional genes in forests (Northeast China). [PDF]

Front Microbiol
Jia W, Shu Y, Zhao P, Zhou M, Yue Y.
europepmc   +1 more source

Indispensable Gene Functions in Neurospora [PDF]

Proceedings of the National Academy of Sciences, 1953
K C, Atwood, F, Mukai
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Enhanced Biohydrogen Production through Dark Fermentation by Humic Acid: Insights into Microbial Composition and Functional Genes. [PDF]

J Microbiol Biotechnol
Zhang L, Bai Y, Sang J, Dong J, Wu X, Ban Q.   +5 more
europepmc   +1 more source

Enrichment of differentially expressed gene signatures in Hallmark functional annotation categories.

, 2016
Roman Kosoy, Charuta Agashe, Grishin Alexander, Y. Leung Donald, Wood Robert A., Sicherer Scott H., Jones Stacie M., Burks A. Wesley, Davidson Wendy F., Lindblad Robert W., Dawson Peter, M.S. Merad, A. Kidd Brian, T. Dudley Joel, A. Sampson Hugh, Cecilia Berin M.   +15 more
openalex   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Pangenomic insights into Dehalobacter evolution and acquisition of functional genes for bioremediation. [PDF]

Microb Genom
Bulka O, Mahadevan R, Edwards EA.
europepmc   +1 more source

Regulating Microbial Community and Functional Genes to Mitigate Ammonia And Nitrous Oxide Emissions And Facilitate Savoy Cabbage Growth: Impact of Partial Wool Organic Fertilizer Substitution

Jiahui Wang, Caixia Sun, Shuyan Li, Yixun Shi, Hui Li, Junlong Song, Jing Yuan, Wenhai Luo, Guoxue Li, Wen Liu, Guoxiang Bu, Hongbin Wang, Lianhui Shi   +12 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source